Alendon Tablet 70 mg contains Alendronic Acid, a bisphosphonate used in the prevention and treatment of bone loss disorders. It is primarily prescribed for osteoporosis in postmenopausal women and in men at high risk of fractures. Alendon Tablet 70 mg helps strengthen bones, increases bone mineral density, and significantly reduces the risk of vertebral and hip fractures when taken as directed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Alendon Tablet 70 mg is indicated for:

• Treatment and prevention of osteoporosis in postmenopausal women

• Osteoporosis in men

• Glucocorticoid-induced osteoporosis

• Paget’s disease of bone

Therapeutic Class

Bisphosphonate

Pharmacology

Alendronic Acid is a nitrogen-containing bisphosphonate that inhibits osteoclast-mediated bone resorption. It binds strongly to hydroxyapatite in bone, particularly at sites of active bone remodeling. By inhibiting osteoclast activity, alendronic acid reduces bone turnover, allowing osteoblasts to build new bone more effectively. This results in increased bone mineral density and improved bone strength, thereby lowering the risk of fractures.

Dosage and Administration

Osteoporosis:

• Recommended dose: 70 mg once weekly

Paget’s disease of bone:

• Dose may vary as prescribed by the physician

Administration instructions are critical for safety and effectiveness:

• Take the tablet in the morning after waking up, on an empty stomach

• Swallow whole with a full glass of plain water

• Do not chew, suck, or crush the tablet

• Remain upright (sitting or standing) for at least 30 minutes after taking the tablet

• Avoid food, beverages, or other medications for at least 30 minutes after dosing

Drug Interactions

Alendon Tablet 70 mg may interact with:

• Calcium supplements

• Antacids

• Iron preparations

• Nonsteroidal anti-inflammatory drugs

These agents may reduce absorption or increase gastrointestinal irritation if taken together.

Contraindications

Alendon Tablet 70 mg is contraindicated in patients with:

• Abnormalities of the esophagus that delay esophageal emptying

• Inability to stand or sit upright for at least 30 minutes

• Hypocalcemia

• Hypersensitivity to alendronic acid

Side Effects

Common side effects include:

• Abdominal pain

• Dyspepsia

• Esophageal irritation

• Nausea

• Musculoskeletal pain

Rare but serious side effects may include esophagitis, esophageal ulceration, osteonecrosis of the jaw, and atypical femoral fractures with long-term use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Correct hypocalcemia and vitamin D deficiency before initiating therapy

• Use with caution in patients with renal impairment or gastrointestinal disorders

• Maintain adequate intake of calcium and vitamin D during treatment

• Dental examination is advised prior to long-term therapy

Pregnancy and Lactation

Alendon Tablet 70 mg is not recommended during pregnancy and breastfeeding due to potential risk to the fetus or infant.

Storage Conditions

Store in a cool, dry place away from moisture and direct sunlight.
Keep out of reach of children.