Teviral Tablet 0.5 mg contains Entecavir, a potent antiviral medication used for the treatment of chronic hepatitis B virus (HBV) infection. It belongs to the class of nucleoside analog reverse transcriptase inhibitors (NRTIs) and works by preventing the replication of HBV in the liver, helping to reduce viral load, liver inflammation, and the risk of progression to cirrhosis or liver cancer.

Entecavir is highly effective in suppressing HBV DNA, improving liver function, and maintaining long-term viral suppression in patients with chronic hepatitis B.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Teviral Tablet is indicated for:

• Chronic hepatitis B infection in adults and children (aged ≥2 years) with evidence of active viral replication
• Prevention of liver disease progression, including cirrhosis and hepatocellular carcinoma
• Patients with compensated or decompensated liver disease due to HBV

Mechanism of Action

Entecavir is a guanosine nucleoside analog that inhibits hepatitis B viral reverse transcriptase. It works by:

• Blocking viral DNA synthesis
• Suppressing viral replication in hepatocytes
• Reducing liver inflammation and damage

This results in decreased HBV viral load and improved liver function over time.

Dosage and Administration

• The usual adult dose is 0.5 mg once daily on an empty stomach (at least 2 hours before or after food).
• Duration of therapy depends on viral load, liver function, and patient response. Long-term therapy may be required in chronic cases.
• Swallow the tablet whole with water; do not crush or chew.
• Dose adjustments may be necessary in patients with renal impairment.

Benefits

• Effectively suppresses hepatitis B viral replication
• Reduces liver inflammation and risk of fibrosis or cirrhosis
• Lowers risk of hepatocellular carcinoma in chronic HBV patients
• Well-tolerated with a low incidence of serious side effects
• Convenient once-daily oral dosing

Side Effects

Common side effects may include:

• Headache
• Fatigue
• Nausea
• Dizziness

Serious but rare side effects:

• Lactic acidosis
• Severe liver problems
• Kidney function impairment
• Allergic reactions

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Monitor liver and kidney function before and during therapy.
• Use caution in patients with pre-existing renal or hepatic impairment.
• May cause lactic acidosis in rare cases, particularly in patients with liver disease.
• Abrupt discontinuation can result in HBV flare; always consult a physician before stopping therapy.
• Pregnancy and breastfeeding should only use under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Teviral Tablet may interact with:

• Other antiviral medications
• Nephrotoxic drugs (monitor kidney function)
• Drugs that affect liver metabolism

Always inform your healthcare provider of all medications, supplements, or herbal products you are taking.

Storage

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.