Trigent Capsule 200 mg contains Fenofibrate, a lipid-lowering medication used to manage high cholesterol and triglyceride levels in the blood. It is primarily prescribed for patients with hypertriglyceridemia, mixed dyslipidemia, or hypercholesterolemia who are at risk of cardiovascular diseases such as heart attack and stroke.

Fenofibrate works by helping the body break down fats more efficiently, lowering levels of triglycerides and improving high-density lipoprotein (HDL) cholesterol. It is commonly used in combination with lifestyle changes, including diet, exercise, and weight management, to achieve optimal lipid control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Fenofibrate

• Strength: 200 mg per capsule

• Dosage Form: Oral capsule

• Pharmacological Class: Fibrate (Lipid-lowering agent)

Mechanism of Action

Fenofibrate activates peroxisome proliferator-activated receptor alpha (PPARα), which regulates lipid metabolism in the liver. Activation of PPARα leads to:

• Increased breakdown of triglyceride-rich particles

• Reduced production of very low-density lipoprotein (VLDL)

• Increased levels of protective high-density lipoprotein (HDL)

This dual action helps reduce harmful lipids and improve overall cardiovascular health.

Indications

Trigent Capsule 200 mg is indicated for:

• Treatment of high triglyceride levels (hypertriglyceridemia)

• Management of high cholesterol (hypercholesterolemia)

• Mixed lipid disorders (combined high cholesterol and triglycerides)

• Reducing cardiovascular risk in patients with dyslipidemia

Dosage and Administration

• The usual recommended dose is 200 mg once daily, or as prescribed by a physician.

• The capsule should be swallowed whole with water, preferably after meals to enhance absorption.

• Dosage adjustments should be made based on blood lipid levels and kidney function.

• Patients should continue regular dietary and lifestyle measures while taking this medication.

Benefits

• Effectively lowers triglycerides and LDL cholesterol

• Increases HDL (“good”) cholesterol

• Helps prevent cardiovascular complications such as heart attack and stroke

• Supports long-term management of dyslipidemia

• Suitable for use with lifestyle modifications for optimal results

Possible Side Effects

Trigent Capsule is generally well tolerated, but some patients may experience:

Common side effects:

• Stomach upset or abdominal pain

• Nausea

• Headache

• Muscle pain (myalgia)

Rare but serious side effects:

• Liver enzyme abnormalities

• Muscle inflammation (myopathy)

• Gallstones

Patients should consult their doctor if they experience severe muscle pain, weakness, or yellowing of the skin/eyes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with kidney or liver impairment.

• Regular monitoring of liver function and kidney function is recommended during treatment.

• Inform your doctor about any current medications, especially statins, to avoid interactions.

• Pregnant or breastfeeding women should use this medication only under medical supervision.

Storage

• Store in a cool, dry place below 30°C.

• Protect from moisture and light.

• Keep out of reach of children.