Coxitor Tablet 120 mg contains Etoricoxib, a selective COX-2 inhibitor belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used for the management of moderate to severe pain and inflammation in various acute and chronic musculoskeletal conditions. The higher strength formulation provides effective and long-lasting relief from pain, stiffness, and swelling while offering improved gastrointestinal safety compared to non-selective NSAIDs.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Etoricoxib 120 mg

Mechanism of Action

Etoricoxib selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which plays a key role in the synthesis of prostaglandins responsible for pain and inflammation. By blocking COX-2 activity, Coxitor Tablet reduces inflammatory responses, decreases swelling, and relieves pain without significantly inhibiting COX-1, which helps protect the gastric mucosa.

Indications

Coxitor Tablet 120 mg is commonly indicated for:

• Acute pain conditions requiring strong analgesia
• Osteoarthritis with severe symptoms
• Rheumatoid arthritis
• Ankylosing spondylitis
• Acute gouty arthritis attacks
• Post-operative dental or orthopedic pain
• Musculoskeletal pain and inflammatory disorders

Dosage and Administration

• The dosage must be prescribed by a qualified healthcare professional.
• Usually administered once daily, with or without food.
• The lowest effective dose for the shortest possible duration is recommended.
• Not intended for long-term continuous use without medical supervision.

Contraindications

Coxitor Tablet should not be used in patients with:

• Known hypersensitivity to Etoricoxib or other NSAIDs
• Active gastrointestinal ulceration or bleeding
• Severe hepatic or renal impairment
• Uncontrolled hypertension or significant cardiovascular disease
• Pregnancy and breastfeeding unless clearly advised by a physician

Side Effects

Possible adverse effects include:

• Headache and dizziness
• Nausea or indigestion
• Abdominal pain
• Fluid retention or edema
• Increased blood pressure
• Fatigue
• Rare but serious cardiovascular thrombotic events with prolonged use

Precautions

• Caution is required in patients with cardiovascular risk factors
• Blood pressure should be monitored regularly during treatment
• Avoid concurrent use with other NSAIDs unless prescribed
• Use carefully in elderly patients and those with liver or kidney impairment
• Long-term therapy should only be undertaken under strict medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Coxitor Tablet 120 mg may interact with:

• Anticoagulants such as warfarin
• Diuretics and antihypertensive agents
• Lithium preparations
• Methotrexate
• Other NSAIDs, increasing risk of side effects

Storage Conditions

• Store below 30°C in a dry place
• Keep away from direct sunlight and moisture
• Keep out of reach of children