Tetrazin Tablet 12.5 mg contains Tetrabenazine, a medication primarily used to manage movement disorders associated with neurological conditions. It is especially effective in reducing involuntary movements (chorea) seen in disorders such as Huntington’s disease. By regulating certain brain chemicals, Tetrazin helps improve motor control and enhances the patient’s quality of life.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tetrazin Tablet is indicated for:

• Chorea associated with Huntington’s disease
• Hyperkinetic movement disorders
• Tardive dyskinesia (as per physician’s advice)
• Other involuntary movement conditions

Mechanism of Action

Tetrabenazine works by depleting monoamines such as dopamine, serotonin, and norepinephrine in the brain. It specifically inhibits vesicular monoamine transporter type 2 (VMAT2), leading to:

• Reduced dopamine storage in nerve terminals
• Decreased abnormal involuntary movements
• Improved motor control

This action helps stabilize excessive motor activity seen in neurological disorders.

Dosage and Administration

• The initial dose is usually 12.5 mg once or twice daily, which may be gradually increased based on patient response and tolerance.
• Dosage adjustments should be made cautiously under medical supervision.
• It should be taken with food to improve tolerability.
• Do not abruptly stop the medication without consulting a doctor.

Benefits

• Effectively reduces involuntary movements (chorea)
• Improves daily functioning and quality of life
• Helps manage symptoms of complex neurological disorders
• Flexible dosing allows individualized treatment

Side Effects

Common side effects may include:

• Drowsiness or sedation
• Fatigue
• Depression
• Insomnia
• Nausea

Serious side effects:

• Severe depression or suicidal thoughts
• Parkinsonism (rigidity, tremors)
• QT prolongation (heart rhythm changes)

Immediate medical attention is required if serious symptoms occur.

Precautions and Warnings

• Contraindicated in patients with untreated or severe depression
• Monitor for mood changes and suicidal thoughts
• Use cautiously in patients with liver impairment
• Avoid alcohol and other sedatives
• Not recommended during pregnancy or breastfeeding unless clearly needed
• Regular follow-up is essential during treatment

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Tetrazin Tablet may interact with:

• Antidepressants (especially MAO inhibitors)
• Antipsychotic medications
• Sedatives or CNS depressants
• Drugs affecting heart rhythm

Always inform your doctor about all medications being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.