Tizabet Capsule 200 mg contains Fenofibrate, a lipid-lowering agent belonging to the fibrate class. It is primarily used to manage dyslipidemia, including elevated triglycerides, high cholesterol, and mixed lipid disorders. Fenofibrate works by activating peroxisome proliferator-activated receptor alpha (PPAR-α), which increases the breakdown of triglycerides and helps raise HDL (“good”) cholesterol levels.

Tizabet helps reduce the risk of cardiovascular complications associated with abnormal lipid levels and supports overall heart health as part of a comprehensive treatment plan including diet, exercise, and lifestyle changes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Tizabet Capsule is indicated for:

• Hypertriglyceridemia (high triglycerides)
• Mixed dyslipidemia (elevated LDL cholesterol and triglycerides)
• Low HDL cholesterol levels
• Prevention of cardiovascular events in patients with lipid abnormalities
• Patients who have not achieved adequate lipid control with diet and lifestyle measures alone

Mechanism of Action

Fenofibrate, the active ingredient in Tizabet, works by:

• Activating PPAR-α, which increases lipoprotein lipase activity
• Enhancing the breakdown of triglyceride-rich lipoproteins
• Increasing HDL (“good”) cholesterol levels
• Reducing LDL (“bad”) cholesterol and very low-density lipoproteins (VLDL)

These effects lead to improved lipid profiles, lowering the risk of atherosclerosis and cardiovascular complications.

Dosage and Administration

• Typical dose: 1 capsule (200 mg) once daily, preferably with meals for better absorption.
• Dose may be adjusted based on lipid levels and physician recommendations.
• Take consistently at the same time each day to maintain stable blood levels.
• Should be used in conjunction with diet, exercise, and lifestyle modification.

Benefits

• Lowers triglycerides and LDL cholesterol
• Raises HDL cholesterol
• Reduces the risk of atherosclerosis and cardiovascular complications
• Supports comprehensive management of dyslipidemia
• Convenient once-daily dosing

Side Effects

Common side effects may include:

• Mild gastrointestinal discomfort (nausea, abdominal pain, diarrhea)
• Headache
• Muscle pain or cramps (myalgia)
• Elevated liver enzymes in some patients

Serious but rare side effects:

• Rhabdomyolysis (severe muscle breakdown)
• Liver toxicity or hepatitis
• Pancreatitis
• Allergic reactions

Seek medical attention if severe muscle pain, jaundice, or unusual fatigue occurs.

Precautions and Warnings

• Not recommended in patients with severe liver or kidney impairment
• Caution in patients with a history of gallbladder disease
• Regular monitoring of liver function tests and kidney function is advised
• Pregnancy and breastfeeding: consult a healthcare professional before use
• Inform your doctor if taking other lipid-lowering medications to prevent interactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Fenofibrate may interact with:

• Statins (increased risk of muscle-related side effects)
• Anticoagulants (may increase bleeding risk)
• Immunosuppressants like cyclosporine
• Other fibrates or niacin

Always inform your healthcare provider about all medications and supplements being taken.

Storage

• Store below 25°C in a dry, cool place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after the expiration date.