Uptiva Tablet 150 mg is a prescription medication designed to improve wakefulness in adults experiencing excessive sleepiness. It contains Armodafinil, a well-established wakefulness-promoting agent, commonly prescribed for conditions such as narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). Uptiva helps patients stay alert and focused during the day, enhancing productivity and quality of life.

Armodafinil, the active ingredient, is a purified enantiomer of modafinil, offering a longer duration of action with a consistent wake-promoting effect. Uptiva 150 mg works on specific areas of the brain involved in sleep-wake regulation, promoting alertness without the severe stimulant effects typically associated with traditional psychostimulants.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Uptiva Tablet 150 mg is indicated for:

• Narcolepsy: To reduce excessive daytime sleepiness in patients with this neurological sleep disorder.

• Obstructive Sleep Apnea (OSA): Used alongside primary treatments like CPAP to improve wakefulness.

• Shift Work Sleep Disorder (SWSD): Helps patients maintain alertness during atypical work schedules, especially night or rotating shifts.

Therapeutic Class

CNS Stimulant / Wakefulness-promoting agent

Pharmacology

Armodafinil, the active component of Uptiva, acts on the central nervous system to enhance alertness. Though its precise mechanism is not fully understood, it is believed to modulate neurotransmitters such as dopamine, norepinephrine, and histamine, which play critical roles in regulating the sleep-wake cycle.

Following oral administration, Uptiva 150 mg is well absorbed, with peak plasma concentrations achieved in approximately 2 hours. The drug is extensively metabolized in the liver and excreted primarily via urine. Its long half-life allows for sustained wake-promoting effects throughout the day, making it ideal for patients with chronic sleepiness.

Dosage and Administration

• Narcolepsy and OSA: 150 mg to 250 mg once daily in the morning.

• Shift Work Sleep Disorder: 150 mg approximately 1 hour before the start of the work shift.

Uptiva should be taken orally with or without food. It is important to avoid taking the tablet late in the day to prevent insomnia. Dosage adjustments may be required for patients with severe liver impairment. The tablet should be swallowed whole with water and not crushed or chewed.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

Uptiva Tablet 150 mg is contraindicated in:

• Patients with a known hypersensitivity to Armodafinil or modafinil.

• Individuals with a history of left ventricular hypertrophy, arrhythmias, or severe cardiac conditions unless under careful medical supervision.

• Patients with a history of drug or alcohol dependence should use caution.

Side Effects

Common side effects may include:

• Headache

• Nausea or vomiting

• Dizziness

• Insomnia

• Dry mouth

Serious adverse effects, though rare, may include severe rash, psychiatric symptoms such as anxiety, agitation, or hallucinations, and cardiovascular events. Any unusual or persistent side effects should be reported to a healthcare professional immediately.

Precautions and Warnings

• Use with caution in patients with hypertension or cardiac disorders.

• May impair judgment, so avoid activities requiring full alertness until the drug’s effects are known.

• Uptiva is not a substitute for adequate sleep, and underlying sleep disorders should be managed.

• Not recommended for children under 18 years of age.

Pregnancy and Lactation

Uptiva should be used during pregnancy only if the potential benefit outweighs the risk. It is not recommended during lactation due to unknown effects on breastfed infants.

Storage Conditions

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.