Lesovir-C Tablet is a fixed-dose combination antiviral medicine containing Ledipasvir 90 mg and Sofosbuvir 400 mg. It is used for the treatment of chronic Hepatitis C virus (HCV) infection in adult patients. This advanced direct-acting antiviral (DAA) therapy offers a highly effective, well-tolerated, and interferon-free treatment option for eligible patients, helping achieve sustained virologic response (SVR), which is considered a cure for hepatitis C.

Lesovir-C Tablet is widely prescribed due to its high cure rates, simple once-daily dosing, and favorable safety profile. It plays a vital role in reducing liver inflammation, preventing disease progression, and lowering the risk of serious complications such as liver cirrhosis and hepatocellular carcinoma.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Indications

Lesovir-C Tablet is indicated for the treatment of:

• Chronic Hepatitis C infection

• Hepatitis C virus genotype 1, 4, 5, or 6

• Patients with or without compensated liver disease

• Selected patients with compensated cirrhosis, as advised by a specialist

Treatment duration and suitability depend on viral genotype, prior treatment history, and liver condition.

Mechanism of Action

Lesovir-C Tablet works by combining two potent antiviral agents that target different stages of the Hepatitis C virus life cycle:

• Ledipasvir is an NS5A inhibitor that interferes with viral RNA replication and assembly of new virus particles.

• Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor that blocks viral RNA synthesis.

By inhibiting viral replication at multiple points, Lesovir-C effectively suppresses the virus, allowing the body to clear the infection and achieve long-term viral eradication.

Key Benefits

• High cure rates for chronic Hepatitis C

• Once-daily oral dosing for better patient compliance

• Interferon-free regimen with improved tolerability

• Short treatment duration in many patients

• Helps prevent progression to cirrhosis and liver cancer

Dosage and Administration

• Adults: One tablet once daily, with or without food, or as prescribed by a healthcare professional.

• Tablets should be swallowed whole and taken at the same time each day.

• Treatment duration is usually 12 weeks, but may vary based on clinical factors.

Patients should strictly follow the prescribed regimen to ensure optimal treatment outcomes.

Precautions and Warnings

• Not recommended for patients with severe renal impairment unless advised by a specialist.

• Caution is required when co-administered with medicines that may interact, such as certain antacids, anticonvulsants, or herbal products.

• Screening for Hepatitis B is recommended before starting therapy, as reactivation may occur.

• Use during pregnancy or breastfeeding should be based on medical advice.

• Regular monitoring of liver function and viral load is advised during treatment.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Conditions

Store Lesovir-C Tablet in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.