Daomin Tablet 500 mg (Metformin Hydrochloride)

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Daomin Tablet 500 mg contains Metformin Hydrochloride, a widely used oral antidiabetic medication primarily prescribed for type 2 diabetes mellitus. Metformin belongs to the biguanide class and works by improving the body’s sensitivity to insulin and reducing hepatic glucose production, helping maintain stable blood sugar levels. It is especially beneficial for patients who are overweight or have insulin resistance. Daomin Tablet 500 mg is suitable for adults and adolescents over 10 years of age and is considered a first-line therapy for effective glycemic control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

  • Active Ingredient: Metformin Hydrochloride 500 mg

  • Dosage Form: Oral tablet

  • Route of Administration: Oral

Mechanism of Action

Metformin lowers blood glucose levels through multiple mechanisms:

  • Reduction of hepatic glucose production: Metformin decreases gluconeogenesis in the liver, which lowers fasting blood sugar levels.

  • Improved insulin sensitivity: It enhances peripheral glucose uptake in muscle and adipose tissues, increasing the body’s response to insulin.

  • Reduction of intestinal glucose absorption: Metformin slightly decreases the absorption of glucose from the gut.

Unlike sulfonylureas, Metformin does not stimulate insulin secretion, reducing the risk of hypoglycemia when used alone.

Indications

Daomin Tablet 500 mg is indicated for:

  • Management of type 2 diabetes mellitus in adults and adolescents over 10 years

  • Patients with inadequate glycemic control despite diet and exercise

  • Use as monotherapy or in combination with other oral antidiabetic agents or insulin

  • Obese patients with insulin resistance or metabolic syndrome

  • Prevention of long-term complications of diabetes, including cardiovascular disease, nephropathy, neuropathy, and retinopathy

Dosage and Administration

  • Initial dose for adults: 500 mg once or twice daily with meals to minimize gastrointestinal side effects

  • Dose may be gradually increased based on blood glucose levels, up to a maximum of 2,000–2,500 mg per day in divided doses

  • Swallow the tablet with water; do not crush or chew extended-release formulations

  • Maintain a consistent diet, exercise, and monitoring schedule for optimal results

  • Regular blood sugar monitoring is essential for dose adjustment

Contraindications

Daomin Tablet 500 mg should not be used in:

  • Patients with hypersensitivity to Metformin or biguanides

  • Severe renal impairment or acute kidney injury

  • Conditions associated with hypoxia, such as acute heart failure or respiratory insufficiency

  • Hepatic impairment or alcohol abuse

  • Diabetic ketoacidosis or lactic acidosis

Precautions and Warnings

Possible Side Effects

Daomin Tablet is generally well tolerated. Common side effects include:

  • Gastrointestinal disturbances: nausea, vomiting, diarrhea, and abdominal discomfort

  • Mild metallic taste

  • Rare but serious: lactic acidosis, especially in patients with renal impairment

Storage

Store below 30°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Conclusion

Daomin Tablet 500 mg is an effective and safe option for managing type 2 diabetes mellitus. By improving insulin sensitivity and reducing hepatic glucose production, it helps maintain stable blood sugar levels and reduces the risk of long-term complications. When combined with diet, exercise, and regular monitoring, Daomin Tablet 500 mg provides reliable glycemic control under medical supervision.

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Daomin Tablet 500 mg (Metformin Hydrochloride)
Daomin Tablet 500 mg (Metformin Hydrochloride)
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