Ferasirrox Tablet 250 mg contains Deferasirox, an effective oral iron chelator used to manage chronic iron overload in patients who require frequent blood transfusions. Conditions such as thalassemia major, sickle cell disease, and myelodysplastic syndromes often necessitate repeated transfusions, leading to excessive accumulation of iron in the body. If left untreated, iron overload can damage vital organs, including the heart, liver, and endocrine glands, potentially resulting in cardiomyopathy, liver cirrhosis, diabetes, and hormonal imbalances.

Ferasirrox Tablet 250 mg works by binding excess iron in the bloodstream and facilitating its excretion through the feces, thereby reducing iron levels and minimizing the risk of organ damage. Its oral formulation provides a convenient alternative to intravenous chelation therapies, ensuring better compliance and ease of long-term management. This dose is particularly suitable for patients with moderate iron overload or those requiring dose titration.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features and Benefits

Active Ingredient:

• Deferasirox 250 mg per tablet

Effective Iron Chelation:

• Reduces transfusion-related iron accumulation

• Protects vital organs from iron-induced damage

• Helps maintain normal iron levels for improved long-term health

Convenient Oral Therapy:

• Once-daily tablet for easy administration

• Avoids the need for intravenous therapy

• Supports patient adherence and comfort

Organ Protection:

• Prevents cardiac complications, liver damage, and endocrine dysfunction

• Helps reduce morbidity and prolong survival

• Supports overall quality of life in chronically transfused patients

Flexible Dosing:

• Dose can be adjusted based on body weight, transfusion requirements, and serum ferritin levels

• Regular monitoring ensures optimal safety and effectiveness

How It Works

Deferasirox, the active component of Ferasirrox, functions as a tridentate iron chelator. Its mechanism of action involves:

1. Iron Binding: Selectively binds free iron (Fe³⁺) circulating in the bloodstream.

2. Complex Formation: Forms a stable, water-soluble iron-deferasirox complex.

3. Excretion: Facilitates elimination of excess iron primarily via feces, lowering systemic iron stores.

By removing excess iron, Ferasirrox Tablet 250 mg helps prevent organ toxicity associated with chronic transfusion therapy and maintains overall health.

Indications

Ferasirrox Tablet 250 mg is indicated for:

• Treatment of chronic iron overload in transfusion-dependent patients with thalassemia major

• Management of iron accumulation in sickle cell disease and myelodysplastic syndromes

• Patients at risk of organ damage due to repeated blood transfusions

• Long-term prevention of cardiac, hepatic, and endocrine complications associated with iron overload

Dosage and Administration

• Take once daily orally, as prescribed by a healthcare professional.

• Swallow the tablet whole with water, preferably on an empty stomach or at least 30 minutes before food.

• Dosage is individualized based on body weight, transfusion history, and serum ferritin levels.

• Regular monitoring of serum ferritin, liver function, and kidney function is essential.

• Do not abruptly stop therapy, as iron levels can accumulate rapidly.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Safety Information

• Inform your doctor if you have liver or kidney disease, gastrointestinal disorders, or hypersensitivity to Deferasirox.

• Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, and rash.

• Rare but serious adverse effects can include kidney or liver toxicity, gastrointestinal bleeding, and blood disorders. Seek immediate medical attention if severe symptoms occur.

• Adequate hydration is recommended to minimize kidney-related complications.

• Do not adjust the dose without medical supervision.

Storage Instructions

• Store in a cool, dry place below 30°C.

• Protect from light and moisture.

• Keep out of reach of children.

Ferasirrox Tablet 250 mg provides a safe, effective, and convenient oral therapy for managing chronic iron overload. By reducing systemic iron levels and protecting vital organs, it helps improve long-term outcomes and quality of life in patients dependent on repeated blood transfusions.