Mobifen Suppository 12.5 mg contains Diclofenac Sodium, a non-steroidal anti-inflammatory drug (NSAID) used for pain relief and inflammation control. This rectal suppository formulation is ideal for patients who cannot take oral medication due to nausea, vomiting, or gastrointestinal sensitivity. It provides effective analgesic and anti-inflammatory action by reducing the production of pain- and inflammation-causing prostaglandins.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Diclofenac Sodium 12.5 mg

Mechanism of Action

Diclofenac Sodium inhibits cyclooxygenase (COX-1 and COX-2) enzymes, which are responsible for synthesizing prostaglandins. By lowering prostaglandin levels, Mobifen Suppository reduces pain, inflammation, and swelling in affected tissues. Its rectal administration ensures absorption even in patients with gastrointestinal intolerance to oral NSAIDs.

Indications

Mobifen Suppository 12.5 mg is indicated for:

• Acute pain relief
• Musculoskeletal pain (sprains, strains)
• Post-operative pain management
• Pain from inflammation in patients unable to take oral NSAIDs
• Fever and discomfort associated with inflammatory conditions

Dosage and Administration

• Adults: 1 suppository rectally, 1–2 times daily or as directed by a physician
• Insert the suppository gently into the rectum after cleaning the area
• Use the minimum effective dose for the shortest duration necessary
• Avoid exceeding the prescribed dose

Benefits

• Provides effective pain relief and anti-inflammatory action
• Suitable for patients unable to take oral medication
• Rapid absorption via rectal route
• Convenient and easy-to-use formulation
• Helps manage acute and post-operative pain

Side Effects

Common side effects:

• Mild rectal irritation
• Nausea or abdominal discomfort
• Headache or dizziness

Serious side effects (rare):

• Gastrointestinal bleeding or ulceration
• Kidney or liver impairment
• Severe allergic reactions (rash, swelling, difficulty breathing)
• Cardiovascular complications with prolonged use

Precautions

• Use with caution in patients with gastrointestinal, kidney, or liver disorders
• Avoid prolonged use to reduce risk of side effects
• Monitor renal and liver function in patients on long-term therapy
• Consult a doctor if symptoms persist or worsen
• Elderly patients may be more sensitive to adverse effects

Contraindications

• Hypersensitivity to Diclofenac or other NSAIDs
• Active gastrointestinal bleeding or ulcer
• Severe renal or hepatic impairment
• History of asthma induced by NSAIDs
• Late pregnancy (third trimester)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Diclofenac may interact with:

• Anticoagulants (e.g., warfarin) – increased bleeding risk
• Other NSAIDs – enhanced gastrointestinal side effects
• ACE inhibitors or diuretics – may affect kidney function
• Corticosteroids – increased risk of ulcers or GI irritation

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.