Dicephin Injection 250 mg/vial IV contains Ceftriaxone Sodium, a third-generation cephalosporin antibiotic used for the treatment of a wide range of bacterial infections. It is administered by intravenous (IV) or intramuscular (IM) route under the supervision of a registered healthcare professional. Ceftriaxone is known for its broad-spectrum bactericidal activity and long duration of action, allowing convenient dosing schedules.

Ceftriaxone works by interfering with bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) within the bacterial cell wall, preventing the formation of a stable cell wall and leading to bacterial cell death. It is effective against many Gram-positive and Gram-negative organisms, making it suitable for both hospital-acquired and community-acquired infections.

The 250 mg strength is particularly useful in pediatric cases, mild to moderate infections, or in situations where lower dosing is clinically appropriate as determined by the physician.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dicephin Injection 250 mg/vial is indicated for the treatment of infections caused by susceptible microorganisms, including:

• Respiratory tract infections, including bronchitis and pneumonia

• Urinary tract infections (UTIs)

• Ear, nose, and throat infections

• Skin and soft tissue infections

• Bone and joint infections

• Septicemia

• Meningitis

• Uncomplicated gonorrhea

• Intra-abdominal infections

It may also be used as a prophylactic antibiotic before certain surgical procedures to reduce the risk of postoperative infection.

Dosage and Administration

The dosage depends on the severity of infection, patient age, body weight, and clinical condition.

• Adults: The usual dose ranges from 250 mg to 1 gm once daily or as prescribed by the physician.

• Children and infants: Dose is calculated according to body weight.

• Neonates: Special dosing guidelines must be followed.

The injection should be reconstituted with a suitable diluent as per medical instructions and administered by a healthcare professional only. Self-administration is not recommended.

Precautions

• Contraindicated in patients with known hypersensitivity to ceftriaxone, cephalosporins, or other beta-lactam antibiotics.

• Use with caution in patients with renal or hepatic impairment.

• Caution is advised in patients with a history of gastrointestinal disease, particularly colitis.

• Avoid mixing or administering with calcium-containing solutions in neonates.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Most patients tolerate Dicephin well. However, some may experience:

• Pain or swelling at the injection site

• Diarrhea

• Nausea or vomiting

• Rash or allergic reactions

• Elevated liver enzymes

Serious hypersensitivity reactions are rare but require immediate medical attention.

Storage Instructions

Store below 25°C in a cool, dry place away from light. Keep out of reach of children. Use the reconstituted solution within the recommended time period.

Dicephin Injection 250 mg/vial provides effective and reliable antibacterial coverage when prescribed appropriately by a healthcare professional.