Xyotil 40 contains Olmesartan, an angiotensin II receptor blocker (ARB) used to manage hypertension (high blood pressure). By selectively inhibiting angiotensin II at its receptor sites, Xyotil helps relax blood vessels, lower peripheral resistance, and reduce blood pressure, thereby decreasing the risk of stroke, heart attack, and kidney complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Antihypertensive Agent

• Angiotensin II Receptor Blocker (ARB)

Indications

Xyotil 40 is prescribed for the treatment of hypertension in adults. It can be used:

• As monotherapy to lower elevated blood pressure

• In combination with other antihypertensive agents when monotherapy is insufficient

Dosage & Administration

• Starting dose: 20 mg once daily for most patients

• Titration: If further blood pressure reduction is needed after 2 weeks, increase to 40 mg once daily

• Maximum dose: 40 mg per day (higher doses do not provide additional benefit)

• Can be taken with or without food

• Pediatric use: Safety and efficacy not established

Special Considerations:

• Patients with volume depletion (e.g., from diuretics) should begin therapy under close medical supervision, possibly starting at a lower dose

• No dose adjustment is needed for elderly patients or those with moderate to severe renal or hepatic impairment

Directions for Use:
Swallow the tablet whole with a glass of water. Do not crush or chew. Follow the dosing instructions provided by your physician. Duration of therapy will depend on your individual condition, age, and response to treatment.

Side Effects

Common (≥1%):

• Dizziness (3% in patients treated with Xyotil vs. 1% with placebo)

Others (similar to placebo):

• Back pain, headache, diarrhea, rhinitis, sinusitis, hyperglycemia, bronchitis, influenza-like symptoms

• Cough: 0.9% incidence, similar to placebo

Drug Interactions

• NSAIDs (including COX-2 inhibitors): May reduce antihypertensive effect and impair renal function; monitor renal function when co-administered

• No clinically significant interactions with digoxin, warfarin, or antacids

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

• Hypersensitivity to Olmesartan or any component of the formulation

• Pregnancy (second and third trimesters) due to risk of fetal injury or death

Pregnancy & Lactation

• Pregnancy: Contraindicated. Discontinue immediately if pregnancy is detected

• Lactation: Olmesartan may be excreted in breast milk; use with caution

Precautions & Warnings

• Monitor renal function in patients with renal impairment or severe heart failure

• Risk of acute renal failure or oliguria in patients dependent on the renin-angiotensin system

• Overdose: Symptoms may include hypotension, tachycardia, or bradycardia. Supportive cardiovascular measures should be provided

Storage

• Store below 30°C in a cool, dry place

• Keep out of the reach and sight of children.