Uliv Tablet 300 mg contains Ursodeoxycholic acid (UDCA), a naturally occurring hydrophilic bile acid widely used in the treatment of hepatobiliary disorders. It is primarily prescribed for dissolving cholesterol gallstones and managing certain chronic liver diseases associated with impaired bile flow (cholestasis).

Uliv 300 mg provides a higher-strength option, suitable for patients requiring moderate to high daily doses based on body weight and clinical condition. It plays a significant role in protecting liver cells, improving bile secretion, and preventing progression of liver damage when used under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Ursodeoxycholic Acid 300 mg

The formulation also includes appropriate pharmaceutical excipients to ensure stability and proper absorption.

Mechanism of Action

Ursodeoxycholic acid exerts its therapeutic effects through several mechanisms:

• Reduction of cholesterol saturation in bile: It decreases intestinal absorption and hepatic secretion of cholesterol, promoting gradual dissolution of cholesterol-rich gallstones.

• Improved bile flow: Stimulates bile secretion and reduces bile stasis in the liver.

• Cytoprotective effect: Replaces toxic hydrophobic bile acids with less toxic hydrophilic bile acids, protecting hepatocytes (liver cells).

• Anti-inflammatory and immunomodulatory properties: Helps reduce liver inflammation in autoimmune and cholestatic liver diseases.

These actions contribute to improved liver function and symptom control in chronic liver conditions.

Indications

Uliv Tablet 300 mg is indicated for:

• Dissolution of small, non-calcified cholesterol gallstones in patients with functioning gallbladder

• Primary biliary cholangitis (PBC)

• Cholestatic liver diseases

• Non-alcoholic fatty liver disease (NAFLD) as advised by a physician

• Intrahepatic cholestasis of pregnancy, under specialist supervision

• Other hepatobiliary disorders requiring bile acid therapy

It is not effective for calcified or pigment stones and is not suitable in cases of complete biliary obstruction.

Dosage and Administration

Dosage is individualized based on body weight and the condition being treated:

• Gallstones: Typically 8–10 mg/kg/day in divided doses

• Chronic liver diseases: Usually 10–15 mg/kg/day or as prescribed

• Tablets should be taken with meals to enhance absorption

• Treatment duration may extend for several months or longer, depending on therapeutic response

Regular monitoring of liver function tests and ultrasound evaluation may be required during therapy.

Precautions and Warnings

• Contraindicated in patients with complete biliary obstruction

• Use cautiously in advanced liver failure

• Periodic liver function monitoring is essential

• Inform your physician about concurrent medications, especially bile acid-binding resins or hormonal therapies

• Use during pregnancy and breastfeeding only if clearly indicated and under medical supervision

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Uliv Tablet is generally well tolerated. Possible side effects include:

• Diarrhea

• Mild abdominal discomfort

• Nausea

• Rare allergic skin reactions

If persistent diarrhea occurs, dosage adjustment may be necessary.

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Conclusion

Uliv Tablet 300 mg (Ursodeoxycholic Acid) is an effective and well-established therapy for cholesterol gallstones and various cholestatic liver diseases. By improving bile composition and protecting liver cells, it supports long-term liver health and helps prevent disease progression when used under medical guidance.