Tyrokin Tablet 100 mg contains Imatinib Mesylate, a targeted anticancer medication used to treat chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other cancers driven by abnormal tyrosine kinase activity. Imatinib is a tyrosine kinase inhibitor that blocks enzymes responsible for cancer cell growth, helping to slow disease progression and improve survival rates.

Tyrokin 100 mg is designed for oral administration, providing a convenient option for dose adjustment, particularly for patients who require lower or incremental doses during treatment. By targeting cancer cells selectively, it minimizes damage to normal cells and supports long-term management of malignancies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Targeted Cancer Therapy: Inhibits BCR-ABL, c-KIT, and PDGF-R tyrosine kinases involved in cancer progression.

• Flexible Dosing: 100 mg tablets allow precise dose adjustments for individual patient needs.

• Oral Convenience: Can be taken at home under medical supervision.

• Improves Prognosis: Slows disease progression and enhances survival in responsive malignancies.

Mechanism of Action

Imatinib Mesylate works by selectively inhibiting tyrosine kinases, including BCR-ABL in CML and c-KIT in GISTs. These enzymes promote uncontrolled cancer cell proliferation. By blocking their activity, Tyrokin prevents tumor growth and induces apoptosis (programmed cell death), helping to manage malignancy effectively.

Indications

Tyrokin Tablet 100 mg is indicated for:

• Chronic Myeloid Leukemia (CML) in chronic, accelerated, or blast phases

• Gastrointestinal Stromal Tumors (GISTs) that are unresectable, recurrent, or metastatic

• Other cancers dependent on tyrosine kinase activity as determined by an oncologist

• Suitable for dose titration or patients requiring lower initial therapy doses

Dosage and Administration

• Dosage is individualized based on the type and stage of cancer, body weight, and response to therapy.

• Tablets are taken orally with water, with or without food.

• Swallow the tablet whole; do not crush or chew.

• Regular monitoring of blood counts, liver, and kidney function is recommended during treatment.

• Dose adjustments may be necessary in case of side effects or concomitant medications.

Precautions

• Use only under the supervision of a qualified oncologist.

• Inform your doctor about any liver, kidney, or heart conditions.

• Do not stop the medication abruptly or adjust the dose without medical advice.

• Pregnant or breastfeeding women should consult a healthcare professional.

• Monitor for potential interactions with other medications, including anticoagulants and CYP3A4 substrates.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea

• Fatigue or weakness

• Muscle cramps or joint pain

• Fluid retention or swelling

• Mild skin rash

Seek immediate medical attention if severe reactions occur, such as liver dysfunction, heart issues, or severe allergic reactions.

Storage

Store in a cool, dry place below 25°C, away from light and moisture. Keep out of reach of children.