Aptin Tablet 50 mg contains Vildagliptin, an oral antidiabetic medication used for the management of type 2 diabetes mellitus. Vildagliptin belongs to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors, which help regulate blood glucose levels by enhancing the body’s natural incretin hormones. These hormones increase insulin release and decrease glucagon secretion, particularly after meals, resulting in better glycemic control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Vildagliptin 50 mg

Mechanism of Action

Vildagliptin works by inhibiting the DPP-4 enzyme, which breaks down incretin hormones such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic peptide). By preventing their degradation:

• Insulin secretion is increased when blood glucose is elevated
• Glucagon secretion is suppressed during hyperglycemia
• This dual action helps maintain stable blood sugar levels, reducing both fasting and postprandial glucose

Indications

Aptin Tablet 50 mg is indicated for:

• Management of type 2 diabetes mellitus in adults
• As monotherapy when diet and exercise alone are insufficient
• In combination with other antidiabetic medications, such as metformin, for improved glycemic control
• Suitable for patients at risk of hypoglycemia when compared to some other antidiabetic drugs

Dosage and Administration

• Typical adult dose: 50 mg once or twice daily, depending on patient needs and physician recommendation
• Can be taken with or without food
• Swallow the tablet whole with water
• Regular monitoring of blood glucose levels is recommended
• Adjustments may be required in patients with kidney or liver impairment

Benefits

• Improves glycemic control without significant risk of hypoglycemia
• Effective in lowering both fasting and postprandial blood glucose
• Can be used alone or with other oral antidiabetic agents
• Well-tolerated, with a favorable safety profile
• Helps support long-term management of type 2 diabetes

Possible Side Effects

Common side effects may include:

• Mild headache
• Dizziness
• Gastrointestinal discomfort such as nausea or diarrhea
• Rarely, hypoglycemia when combined with insulin or sulfonylureas

Serious but rare side effects:

• Severe allergic reactions
• Liver enzyme abnormalities
• Pancreatitis (inflammation of the pancreas)

Precautions and Warnings

• Not recommended for type 1 diabetes or diabetic ketoacidosis
• Use with caution in patients with kidney or liver disease
• Inform your doctor of any existing heart, pancreas, or kidney conditions
• Regular monitoring of blood sugar, kidney, and liver function is advised during therapy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May be combined with metformin, sulfonylureas, or insulin under supervision
• Caution with drugs affecting kidney or liver function
• No significant interactions with common medications, but always consult a physician

Storage Instructions

• Store below 30°C in a cool, dry place
• Protect from moisture and sunlight
• Keep out of reach of children.