Trexam Injection 250 mg/5 ml contains Tranexamic Acid, an antifibrinolytic medicine used to prevent and control excessive bleeding. It helps stabilize blood clots by preventing their breakdown, thereby reducing blood loss in surgical, traumatic, and medical bleeding conditions.

This lower-strength injectable formulation is commonly used in hospitals where dose adjustment is required based on patient condition, body weight, and severity of bleeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml ampoule contains:

• Tranexamic Acid 250 mg

Available as a sterile solution for intravenous administration.

Indications

Trexam Injection 250 mg/5 ml is indicated for:

• Surgical bleeding control (pre- and post-operative)
• Heavy menstrual bleeding (when injectable therapy is required)
• Trauma-related bleeding
• Epistaxis (severe nosebleeds)
• Dental and oral surgical bleeding
• Obstetric and gynecological bleeding under supervision
• Conditions associated with excessive fibrinolysis

Mechanism of Action

Tranexamic Acid works by inhibiting the activation of plasminogen to plasmin, an enzyme responsible for breaking down fibrin clots. By preventing fibrin degradation, it helps maintain stable blood clots and reduces excessive bleeding.

This action supports effective hemostasis and helps minimize blood loss during medical and surgical conditions.

Dosage and Administration

Trexam Injection should only be administered by qualified healthcare professionals.

General guidelines include:

• Given via slow intravenous injection or infusion
• Dose is individualized based on patient condition and bleeding severity
• Administration should be slow to avoid adverse reactions
• Duration of treatment is determined by the physician

Strict medical supervision is required during use.

Benefits of Trexam Injection

• Helps control acute and excessive bleeding
• Stabilizes blood clots effectively
• Useful in surgical and emergency settings
• Reduces need for blood transfusion in some cases
• Can be adjusted easily for patient-specific dosing

Possible Side Effects

Some patients may experience:

• Nausea or vomiting
• Dizziness
• Headache
• Diarrhea
• Injection site irritation

Rare but serious side effects include:

• Blood clots (thromboembolism)
• Visual disturbances
• Hypotension (if injected too quickly)
• Allergic reactions

Immediate medical attention is required if signs of thrombosis occur.

Precautions and Warnings

• Use cautiously in patients with a history of thromboembolic disease
• Not recommended in active blood clotting disorders
• Dose adjustment may be needed in kidney impairment
• Must be administered slowly intravenously
• Avoid unsupervised or long-term use
• Inform the physician about all current medications and medical history

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children
• Use under professional supervision only

Conclusion

Trexam Injection 250 mg/5 ml (Tranexamic Acid) is an effective antifibrinolytic agent used to control and reduce excessive bleeding in surgical, traumatic, and gynecological conditions. By stabilizing blood clots, it helps minimize blood loss and supports safer patient outcomes. Careful medical supervision ensures safe and effective use.