Betacor HZ Tablet combines Bisoprolol Fumarate 2.5 mg, a selective beta-1 blocker, with Hydrochlorothiazide 6.25 mg, a thiazide diuretic, to provide effective management of hypertension. This low-dose combination is ideal for initiating therapy, titrating doses, or treating patients sensitive to higher beta-blocker doses.

The dual-action formulation works synergistically: Bisoprolol reduces heart rate and myocardial oxygen demand, while Hydrochlorothiazide promotes sodium and water excretion, lowering blood volume and vascular pressure. Betacor HZ helps maintain optimal blood pressure, protect the heart, and reduce the risk of cardiovascular complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Benefits

• Lowers high blood pressure through complementary mechanisms
• Reduces heart rate and cardiac workload
• Promotes diuresis to decrease blood volume and vascular resistance
• Supports long-term cardiovascular health
• Suitable for dose initiation or patients requiring gentle beta-blockade

Indications

Betacor HZ Tablet 2.5 mg + 6.25 mg is indicated for:

• Hypertension (high blood pressure)
• Patients needing combination therapy for effective blood pressure control
• Individuals at risk of cardiovascular complications due to uncontrolled hypertension

Mechanism of Action

• Bisoprolol Fumarate (2.5 mg): Selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, cardiac output, and myocardial oxygen demand.
• Hydrochlorothiazide (6.25 mg): Inhibits sodium reabsorption in the distal convoluted tubules, increasing sodium and water excretion, reducing blood volume and blood pressure.
• The combination targets both cardiac and vascular mechanisms, providing additive antihypertensive effects.

Dosage and Administration

• Administer once daily or as prescribed by a physician
• Swallow the tablet whole with water, with or without food
• Do not discontinue abruptly; sudden cessation may worsen hypertension or angina
• Dose adjustments should be guided by a healthcare professional based on blood pressure and heart rate response

Side Effects

Common side effects:

• Fatigue or mild tiredness
• Dizziness or lightheadedness
• Slow heart rate (bradycardia)
• Increased urination due to the diuretic effect

Rare side effects:

• Electrolyte imbalance (low potassium or sodium)
• Swelling of extremities
• Shortness of breath or wheezing in sensitive individuals

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Monitor blood pressure, heart rate, and electrolytes regularly
• Use with caution in patients with kidney or liver disease, diabetes, or severe cardiac conditions
• Inform your physician of all medications being taken to avoid interactions
• Avoid abrupt discontinuation of therapy

Contraindications

• Severe bradycardia or heart block greater than first degree without pacemaker
• Cardiogenic shock or decompensated heart failure
• Hypersensitivity to Bisoprolol, Hydrochlorothiazide, or any component of the tablet
• Severe renal or hepatic impairment without medical supervision

Storage Instructions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep in the original container
• Keep out of reach of children.