Tetrabez Tablet 12.5 mg contains Tetrabenazine, a medication primarily used to treat movement disorders associated with neurological conditions, particularly Huntington’s disease. It helps control involuntary movements such as chorea (sudden, irregular, and uncontrolled movements) that occur due to certain disorders of the nervous system.

Tetrabez works by reducing the levels of specific neurotransmitters in the brain that are responsible for excessive motor activity. By regulating these chemical signals, the medicine helps reduce abnormal movements and improve overall motor control. This can significantly enhance the quality of life for patients suffering from movement-related neurological conditions.

Tetrabez Tablet is usually prescribed as part of a comprehensive treatment plan and should be taken under the supervision of a qualified healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Tetrabenazine

• Strength: 12.5 mg per tablet

• Dosage Form: Oral tablet

• Pharmacological Class: Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

Mechanism of Action

Tetrabenazine works by inhibiting vesicular monoamine transporter type 2 (VMAT2), a protein responsible for transporting neurotransmitters such as dopamine into nerve vesicles.

By blocking VMAT2, the medication reduces the amount of dopamine released in the brain. Lower dopamine activity helps control excessive and involuntary movements associated with neurological disorders.

This mechanism helps stabilize motor activity and reduce the severity of chorea and other abnormal movements.

Indications

Tetrabez Tablet 12.5 mg is indicated for:

• Treatment of chorea associated with Huntington’s disease

• Management of hyperkinetic movement disorders

• Control of involuntary movements caused by neurological conditions

Dosage and Administration

• The dosage should be determined by a physician based on the patient’s condition and response to treatment.

• Treatment usually begins with a low dose, which may be gradually increased to achieve optimal therapeutic effect.

• The tablet should be swallowed whole with water.

• It can be taken with or without food.

• Patients should follow the doctor’s instructions carefully and should not adjust the dose without medical advice.

Benefits

• Helps reduce involuntary movements associated with neurological disorders

• Improves motor control and coordination

• Supports better daily functioning and quality of life

• Provides effective management of Huntington’s disease-related chorea

Possible Side Effects

Like all medications, Tetrabez Tablet may cause side effects in some patients.

Common side effects include:

• Drowsiness

• Fatigue

• Insomnia

• Nausea

• Depression or mood changes

Less common but serious side effects may include:

• Severe depression

• Suicidal thoughts

• Parkinson-like symptoms

• Irregular heartbeat

Patients should seek immediate medical advice if severe or unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with depression or a history of mental health disorders.

• Not recommended for individuals with untreated or severe depression.

• Inform your doctor if you are taking antidepressants, antipsychotics, or other neurological medications.

• Patients should be monitored regularly during treatment to assess response and side effects.

• Avoid driving or operating heavy machinery if the medicine causes drowsiness or dizziness.

Storage

• Store below 30°C in a cool and dry place.

• Protect from light and moisture.

• Keep out of reach of children.