Axita Tablet 5 mg contains Axitinib, a potent oral tyrosine kinase inhibitor (TKI) used in the treatment of advanced renal cell carcinoma (kidney cancer). It works by blocking vascular endothelial growth factor receptors (VEGFR), thereby inhibiting tumor angiogenesis and slowing cancer progression. Axita is typically used in patients with advanced or metastatic disease under oncology supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Axitinib 5 mg per tablet

Mechanism of Action

Axitinib selectively inhibits vascular endothelial growth factor receptors VEGFR-1, VEGFR-2, and VEGFR-3. These receptors play a key role in tumor blood vessel formation (angiogenesis). By blocking these pathways, Axitinib reduces blood supply to the tumor, inhibiting its growth and spread.

Indications

Axita Tablet is indicated for:

• Advanced renal cell carcinoma (RCC) in adults
• Second-line treatment of metastatic kidney cancer after failure of prior therapy
• Combination therapy with immune checkpoint inhibitors (as per oncology protocols)

Dosage and Administration

• Usual starting dose: 5 mg twice daily, or as prescribed by an oncologist
• Dose may be adjusted based on response and tolerability
• Take with or without food
• Swallow tablet whole with water
• Maintain consistent dosing intervals

Benefits

• Helps slow progression of advanced kidney cancer
• Reduces tumor blood supply by inhibiting angiogenesis
• Oral administration improves patient convenience
• Can be used in combination therapy for improved outcomes
• Effective in patients resistant to prior treatments

Possible Side Effects

Common side effects may include:

• Hypertension
• Fatigue
• Diarrhea
• Decreased appetite
• Nausea
• Hoarseness

Less common but serious side effects:

• Blood clots or hemorrhage
• Thyroid dysfunction
• Liver enzyme elevation
• Proteinuria (protein in urine)
• Gastrointestinal perforation (rare but serious)

Precautions and Warnings

• Monitor blood pressure regularly during treatment
• Liver and kidney function tests should be performed periodically
• Use cautiously in patients with cardiovascular disease
• Not recommended during pregnancy or breastfeeding
• Increased risk of bleeding and wound healing complications

Drug Interactions

• CYP3A4 inhibitors or inducers may affect drug levels
• Avoid strong enzyme inducers (e.g., rifampicin, phenytoin)
• Caution with anticoagulants and antihypertensive drugs
• Inform physician about all medications and supplements

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children

Conclusion

Axita Tablet 5 mg (Axitinib) is a targeted cancer therapy used in advanced renal cell carcinoma. By inhibiting tumor angiogenesis, it helps control disease progression and improve patient outcomes when used under strict oncological supervision.