Durogesic Patch 50 mcg/hour contains Fentanyl Citrate, a potent opioid analgesic designed for the management of severe chronic pain that requires continuous, long-term opioid therapy. This transdermal patch delivers a controlled dose of fentanyl over 72 hours, providing consistent pain relief without the need for frequent oral or injectable administration.

Fentanyl is a synthetic opioid that acts directly on the central nervous system to alter the perception and response to pain. Durogesic Patch is particularly indicated for patients with persistent pain due to cancer, severe musculoskeletal disorders, or other chronic pain conditions that are not adequately controlled by non-opioid analgesics. Its transdermal delivery system allows for sustained plasma levels, minimizing fluctuations and improving patient comfort.

The patch is convenient, discreet, and designed for once-every-72-hours application, making it ideal for patients who need continuous pain management while maintaining mobility and daily activities.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Durogesic Patch 50 mcg/hour is indicated for:

• Severe chronic pain requiring long-term opioid therapy

• Pain management in cancer patients

• Patients intolerant or unresponsive to other analgesics

• Situations where oral or injectable opioids are impractical

Key Benefits

• Provides continuous 24-hour pain relief for 72 hours per patch

• Reduces the need for frequent dosing of oral or injectable opioids

• Discreet and easy-to-use transdermal delivery system

• Improves quality of life by maintaining mobility and daily activities

• Ideal for patients with chronic severe pain requiring consistent analgesia

Mechanism of Action

Fentanyl Citrate is a potent mu-opioid receptor agonist. It acts on receptors in the brain, spinal cord, and peripheral nervous system to:

• Inhibit pain signal transmission

• Alter the emotional perception of pain

• Increase pain tolerance

By binding to opioid receptors, fentanyl suppresses the central nervous system’s response to painful stimuli, providing potent analgesic effects even in patients with severe, chronic pain conditions.

Dosage and Administration

• Each patch delivers 50 mcg/hour over a 72-hour period.

• Apply to clean, dry, and hairless skin on the upper torso, upper arm, or chest.

• Rotate application sites to prevent skin irritation.

• Press firmly for 30 seconds to ensure good adhesion.

• Remove the old patch before applying a new one.

• Wash hands after application and avoid exposing the patch to heat sources, which may increase fentanyl absorption.

Important: Durogesic Patch is for opioid-tolerant patients only. Dose adjustments should be made by a healthcare professional.

Precautions

• Use cautiously in patients with respiratory depression, head injury, hypotension, or hepatic/renal impairment.

• Avoid use in opioid-naïve patients due to the risk of life-threatening respiratory depression.

• Do not cut, chew, or ingest the patch.

• Keep away from children, pets, and anyone for whom it is not prescribed.

• Seek immediate medical attention in case of severe drowsiness, difficulty breathing, or signs of overdose.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Drowsiness, dizziness, or lightheadedness

• Nausea, vomiting, or constipation

• Dry mouth or sweating

• Rarely, respiratory depression or bradycardia

Most side effects are dose-dependent and can be managed under medical supervision.

Storage

Store below 30°C in a cool, dry place, protected from moisture and heat. Keep out of reach of children and pets. Dispose of used patches safely to avoid accidental exposure.