Sevel Tablet 800 mg contains Sevelamer Carbonate, a non-calcium, non-metal phosphate binder used to control high blood phosphate levels (hyperphosphatemia) in patients with chronic kidney disease (CKD), especially those on dialysis. Elevated phosphate levels are common in patients with advanced kidney failure and may lead to serious complications such as bone disorders and cardiovascular calcification if left untreated.

Sevelamer Carbonate works by binding dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. The bound phosphate is then eliminated through the feces. By reducing serum phosphate levels, Sevel Tablet helps maintain proper mineral balance and supports long-term bone and cardiovascular health in CKD patients.

Unlike calcium-based phosphate binders, Sevelamer does not increase calcium levels, reducing the risk of hypercalcemia and vascular calcification.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Sevel Tablet 800 mg is indicated for:

• Control of hyperphosphatemia in adult patients with chronic kidney disease on hemodialysis or peritoneal dialysis

• Management of elevated serum phosphate in patients with CKD not yet on dialysis, as advised by a physician

It is usually prescribed as part of a comprehensive treatment plan that includes dietary phosphate restriction.

Mechanism of Action

Sevelamer Carbonate is a polymer that binds phosphate in the digestive tract. It:

• Binds dietary phosphate in the intestine

• Prevents phosphate absorption into the bloodstream

• Reduces serum phosphate levels

• Helps maintain balanced calcium and phosphate levels

By lowering phosphate levels, it helps reduce the risk of bone disease (renal osteodystrophy) and cardiovascular complications in CKD patients.

Dosage and Administration

The dosage of Sevel Tablet 800 mg depends on the patient’s serum phosphate level and dietary phosphate intake. The physician will determine the appropriate starting dose and adjust it based on regular blood test results.

The tablet should be taken with meals to effectively bind phosphate from food. Tablets should be swallowed whole and not crushed or chewed unless advised by a healthcare professional.

Regular monitoring of serum phosphate and calcium levels is essential during treatment.

Precautions and Warnings

• Not indicated for patients with hypophosphatemia (low phosphate levels).

• Use with caution in patients with swallowing difficulties or gastrointestinal disorders.

• May reduce the absorption of certain medications; take other medicines at least 1 hour before or 3 hours after Sevelamer, if recommended.

• Regular laboratory monitoring is necessary to ensure proper mineral balance.

Inform your doctor about all medications and supplements being taken.

Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Diarrhea or constipation

• Abdominal pain

• Indigestion

Most side effects are mild. If severe gastrointestinal symptoms or signs of bowel obstruction occur, seek immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Sevel Tablet 800 mg offers effective phosphate control in patients with chronic kidney disease, supporting safer long-term management of mineral balance and reducing complications associated with elevated phosphate levels.