Pyrostig Tablet 60 mg contains Pyridostigmine Bromide, a cholinesterase inhibitor used to improve muscle strength in conditions associated with neuromuscular transmission disorders. It works by increasing the availability of acetylcholine at neuromuscular junctions, helping enhance muscle contraction and reducing muscle weakness. It is commonly used in the long-term management of myasthenia gravis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pyridostigmine Bromide 60 mg

Indications

Pyrostig Tablet is indicated for:

• Myasthenia gravis (symptomatic treatment)
• Muscle weakness due to neuromuscular disorders
• Post-operative urinary retention (in selected cases)
• Reversal of non-depolarizing neuromuscular blockade (as adjunct use in hospital settings)

Mechanism of Action

Pyridostigmine inhibits acetylcholinesterase, the enzyme responsible for breaking down acetylcholine. This leads to increased levels of acetylcholine at neuromuscular junctions, enhancing nerve impulse transmission and improving skeletal muscle strength and endurance.

Dosage and Administration

• Dosage is individualized based on patient condition and physician guidance.
• Usually taken multiple times daily due to short duration of action.
• Should be taken with or without food as directed.
• Do not adjust dose without medical supervision.

Benefits

• Improves muscle strength and function
• Reduces fatigue associated with myasthenia gravis
• Enhances neuromuscular transmission
• Helps improve daily physical activity and quality of life
• Useful as long-term symptomatic therapy in neuromuscular disorders

Side Effects

Pyrostig Tablet may cause:

• Abdominal cramps
• Increased salivation
• Diarrhea
• Nausea or vomiting
• Muscle twitching
• Excess sweating
• Bradycardia (slow heart rate) in some cases

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with asthma or COPD.
• Monitor in patients with cardiac conditions (risk of bradycardia).
• Avoid overdose as it may lead to cholinergic crisis.
• Use strictly under medical supervision.
• Inform physician about all concurrent medications.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.