Ursolic Suspension 250 mg/5 ml contains Ursodeoxycholic Acid (UDCA) 250 mg per 5 ml, a clinically proven bile acid formulation used for the management of liver and gallbladder disorders. This oral suspension provides an effective, easy-to-administer alternative for patients who have difficulty swallowing tablets or require precise dosage adjustments, including pediatric and elderly patients.

Ursodeoxycholic Acid is widely prescribed to dissolve cholesterol-rich gallstones, improve bile flow, and protect liver cells from damage caused by toxic bile acids. Ursolic Suspension 250 mg/5 ml is particularly valuable in cases of cholestasis, primary biliary cholangitis, and other hepatobiliary disorders, offering both therapeutic and supportive care for liver health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Ursodeoxycholic Acid 250 mg per 5 ml oral suspension

Mechanism of Action

Ursolic Suspension 250 mg/5 ml supports liver and gallbladder function through multiple mechanisms:

1. Cholesterol solubilization – Reduces cholesterol concentration in bile, aiding the gradual dissolution of cholesterol gallstones.

2. Choleretic effect – Stimulates bile secretion from the liver to the intestine, preventing bile stasis and improving digestion.

3. Hepatocyte protection – Shields liver cells from the cytotoxic effects of hydrophobic bile acids.

4. Anti-inflammatory activity – Reduces liver inflammation associated with cholestatic and hepatobiliary disorders.

5. Metabolic support – Maintains a balanced bile acid pool, supporting healthy liver function and overall metabolism.

These actions help in maintaining optimal hepatobiliary health while reducing complications associated with gallstones and cholestasis.

Indications

Ursolic Suspension 250 mg/5 ml is indicated for:

• Cholesterol gallstones – Non-surgical dissolution or prevention of gallstone formation

• Primary biliary cholangitis (PBC) – Management of chronic liver disease associated with bile duct inflammation

• Cholestatic liver disorders – Improvement of bile flow and liver enzyme normalization

• Hepatic protection – Minimizing hepatocyte damage caused by toxic bile acids

• Supportive therapy – General liver and gallbladder health enhancement

It is suitable for both adult and pediatric patients, allowing for flexible dose adjustments based on body weight and clinical condition.

Dosage and Administration

• Adults: Typically 8–10 mg/kg of body weight per day, divided into two or three doses.

• Pediatric patients: Dosage is calculated according to body weight; follow physician guidance.

• Administer orally using a calibrated measuring device to ensure accurate dosing.

• Take after meals to enhance absorption and reduce gastrointestinal discomfort.

• Treatment duration depends on gallstone size, liver enzyme levels, and clinical response, often lasting several months.

• Regular monitoring of liver function is recommended during therapy.

Benefits

• Dissolves cholesterol gallstones naturally

• Enhances bile flow and reduces bile stasis

• Protects liver cells from toxic bile acids

• Reduces liver inflammation and supports hepatobiliary function

• Oral suspension allows flexible dosing for children, elderly, or patients with swallowing difficulties

Precautions

• Avoid use in patients with complete biliary obstruction or acute gallbladder inflammation.

• Use with caution in severe liver failure or hypersensitivity to UDCA.

• Pregnancy and lactation: Only use if clearly indicated by a physician.

• Monitor liver function during prolonged therapy to ensure safety.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Mild gastrointestinal disturbances such as nausea, diarrhea, or abdominal discomfort

• Headache or fatigue

• Rare allergic reactions including rash or itching

Serious side effects are uncommon but require immediate medical attention.

Storage

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep the suspension tightly closed

• Keep out of reach of children

Ursolic Suspension 250 mg/5 ml offers a convenient and effective oral therapy for liver and gallbladder disorders, promoting bile flow, dissolving cholesterol gallstones, and protecting hepatocytes from bile acid-induced damage.