Politrim Tablet 400 mg + 80 mg is a combination antibacterial medicine containing Sulphamethoxazole and Trimethoprim. This well-established dual-action formulation works synergistically to treat a wide range of bacterial infections. By combining two active ingredients that inhibit sequential steps in bacterial folic acid synthesis, Politrim provides enhanced antibacterial effectiveness and helps reduce the risk of resistance.

Sulphamethoxazole belongs to the sulfonamide class of antibiotics and interferes with the formation of dihydrofolic acid in bacteria. Trimethoprim inhibits the enzyme dihydrofolate reductase, preventing the production of tetrahydrofolic acid. Together, these actions block bacterial DNA synthesis, ultimately leading to bacterial cell death.

Politrim Tablet is widely used in the treatment of infections caused by susceptible microorganisms and is effective against both gram-positive and gram-negative bacteria.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Sulphamethoxazole 400 mg

• Trimethoprim 80 mg

Indications

Politrim Tablet 400 mg + 80 mg is indicated for the treatment of:

• Urinary tract infections (UTIs)

• Respiratory tract infections such as bronchitis

• Gastrointestinal infections including certain types of diarrhea

• Ear infections (otitis media)

• Skin and soft tissue infections

• Other infections caused by susceptible bacteria as advised by a physician

Dosage and Administration

Dosage should be determined by a registered healthcare professional based on the type and severity of infection.

• Usually taken twice daily.

• Tablets should be swallowed with a full glass of water.

• It may be taken with or after food to minimize stomach upset.

• Adequate fluid intake is recommended during treatment.

• Complete the full prescribed course even if symptoms improve early.

Do not skip doses or stop therapy prematurely without medical advice.

Precautions and Warnings

• Use cautiously in patients with kidney or liver impairment.

• Not recommended for patients with known hypersensitivity to sulfonamides or trimethoprim.

• Caution is advised in elderly patients and those with folate deficiency.

• May increase sensitivity to sunlight; avoid excessive sun exposure.

• Regular monitoring may be required during prolonged therapy.

Consult your doctor before use during pregnancy or breastfeeding.

Possible Side Effects

Like all antibiotics, Politrim may cause side effects, although not everyone experiences them. Common side effects include:

• Nausea or vomiting

• Loss of appetite

• Skin rash

• Mild gastrointestinal discomfort

• Headache

Seek immediate medical attention if severe allergic reactions, persistent rash, or unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a cool, dry place.

• Protect from light and moisture.

• Keep out of reach of children.

Conclusion

Politrim Tablet 400 mg + 80 mg (Sulphamethoxazole + Trimethoprim) is a trusted and effective antibacterial combination for treating a variety of infections. Its dual mechanism of action provides enhanced bacterial control and reliable therapeutic outcomes when used as directed by a healthcare professional.