Politrim Suspension (200 mg + 40 mg)/5 ml is a combination antibacterial oral suspension containing Sulphamethoxazole and Trimethoprim. This dual-acting formulation is specially designed for pediatric and adult patients who prefer a liquid dosage form. It is widely used for the treatment of various bacterial infections caused by susceptible organisms.

Politrim works through a synergistic mechanism by blocking two sequential steps in the bacterial folic acid synthesis pathway. Sulphamethoxazole, a sulfonamide antibiotic, inhibits the formation of dihydrofolic acid, while Trimethoprim prevents its conversion into tetrahydrofolic acid by inhibiting the enzyme dihydrofolate reductase. This combined action effectively stops bacterial growth and replication, leading to the elimination of infection.

The liquid formulation ensures accurate dosing and easier administration, especially in children and individuals who have difficulty swallowing tablets.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml of suspension contains:

• Sulphamethoxazole 200 mg

• Trimethoprim 40 mg

Indications

Politrim Suspension is indicated for the treatment of:

• Urinary tract infections (UTIs)

• Respiratory tract infections such as bronchitis and pneumonia

• Acute otitis media (middle ear infection)

• Gastrointestinal infections including certain types of bacterial diarrhea

• Skin and soft tissue infections

• Other infections caused by susceptible bacteria as prescribed by a physician

Dosage and Administration

Dosage should be determined by a registered healthcare professional according to the patient’s age, weight, and severity of infection.

• Shake the bottle well before each use.

• Measure the dose accurately using a proper measuring spoon or cup.

• It is usually administered twice daily.

• May be taken with food to reduce stomach upset.

• Ensure adequate fluid intake during treatment.

• Complete the full course of therapy even if symptoms improve early.

Do not discontinue the medication without medical advice.

Precautions and Warnings

• Use cautiously in patients with kidney or liver impairment.

• Contraindicated in patients with known hypersensitivity to sulfonamides or trimethoprim.

• Caution is advised in premature infants and newborns.

• May increase sensitivity to sunlight; avoid prolonged sun exposure.

• Regular monitoring may be required during prolonged therapy.

Consult a doctor before use during pregnancy or breastfeeding.

Possible Side Effects

Some patients may experience side effects, including:

• Nausea or vomiting

• Diarrhea

• Skin rash

• Loss of appetite

• Headache

Severe allergic reactions or persistent symptoms require immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a cool, dry place.

• Protect from light.

• Keep out of reach of children.

• Use within the recommended period after opening.

Conclusion

Politrim Suspension (200 mg + 40 mg)/5 ml (Sulphamethoxazole + Trimethoprim) is a reliable and effective antibacterial medication in liquid form. Its dual mechanism of action provides broad-spectrum coverage against various infections, making it particularly suitable for pediatric and adult patients who require an oral suspension. Always use under proper medical supervision for safe and effective treatment.