Evaglip Tablet 25 mg + 5 mg is a combination antidiabetic medicine containing Empagliflozin and Linagliptin. It is used for the management of type 2 diabetes mellitus in patients who require stronger glycemic control than single-drug therapy.

This higher-dose formulation of empagliflozin provides enhanced glucose-lowering effects, especially in patients with inadequate control on lower doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুনv

Composition

Each tablet contains:

• Empagliflozin 25 mg
• Linagliptin 5 mg

For oral administration.

Mechanism of Action

Evaglip works through two complementary mechanisms:

Empagliflozin (SGLT2 inhibitor)

• Reduces glucose reabsorption in the kidneys
• Increases urinary excretion of glucose
• Helps reduce blood sugar and body weight
• May also provide cardiovascular benefits in some patients

Linagliptin (DPP-4 inhibitor)

• Increases incretin hormone levels (GLP-1, GIP)
• Enhances insulin secretion after meals
• Reduces glucagon secretion
• Helps control post-meal blood sugar spikes

Indications

Evaglip Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients inadequately controlled on diet, exercise, or single therapy
• Combination therapy for improved glycemic control

Dosage and Administration

• Usually taken once daily, with or without food
• Should be taken at the same time each day for best results
• Dose must be prescribed by a physician based on patient condition
• Not recommended for type 1 diabetes or diabetic ketoacidosis

Benefits

Evaglip Tablet offers several benefits:

• Stronger blood sugar control due to higher empagliflozin dose
• Dual mechanism improves fasting and post-meal glucose levels
• May help with modest weight reduction
• Low risk of hypoglycemia when used appropriately
• Convenient once-daily dosing improves adherence

Possible Side Effects

Common side effects include:

• Increased urination
• Urinary tract infections
• Genital fungal infections
• Thirst or dry mouth
• Headache

Less common side effects:

• Dizziness
• Mild dehydration
• Fatigue

Serious side effects:

• Diabetic Ketoacidosis
• Severe urinary or kidney infections
• Acute kidney injury (rare)

Precautions

• Maintain adequate fluid intake to prevent dehydration
• Monitor kidney function regularly
• Use cautiously in elderly patients or those with kidney disease
• Not recommended for type 1 diabetes
• Inform doctor about all medications being used
• Temporary discontinuation may be required during surgery or severe illness

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Evaglip may interact with:

• Diuretics (increased risk of dehydration)
• Insulin or sulfonylureas (risk of hypoglycemia)
• Other antidiabetic drugs

Storage

Store in a cool, dry place below 30°C, protected from moisture and direct sunlight. Keep out of reach of children.