Gefiren Tablet 250 mg contains Gefitinib, a targeted therapy medication used primarily in the treatment of non-small cell lung cancer (NSCLC) with specific genetic mutations. Gefitinib belongs to the class of tyrosine kinase inhibitors (TKIs) and works by blocking the epidermal growth factor receptor (EGFR), which is often overactive in certain cancer cells, leading to uncontrolled growth.

This oral tablet formulation allows patients to take the medication conveniently at home while maintaining consistent therapeutic levels in the bloodstream for effective cancer management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Gefitinib 250 mg

Mechanism of Action

Gefitinib works by:

• Inhibiting EGFR tyrosine kinase, a protein responsible for signaling cancer cells to grow and divide

• Preventing phosphorylation and activation of downstream signaling pathways, leading to decreased cancer cell proliferation

• Inducing apoptosis (programmed cell death) in cancer cells expressing mutated or overactive EGFR

• Selectively targets cancer cells while minimizing effects on normal cells

Indications

Gefiren Tablet 250 mg is indicated for:

• Locally advanced or metastatic non-small cell lung cancer (NSCLC) in patients with EGFR-activating mutations

• First-line therapy for patients with EGFR-mutated NSCLC

• May be prescribed for relapsed or refractory NSCLC after other therapies, under medical supervision

Dosage and Administration

• Adults: Typically 250 mg once daily, or as directed by an oncologist

• Swallow the tablet whole with water; can be taken with or without food

• Maintain a consistent daily schedule for optimal therapeutic effect

• Do not skip or double doses without consulting the physician

• Periodic monitoring of liver function and blood counts is recommended

Precautions

• Use only under oncologist supervision

• Inform your doctor about liver disease, kidney disease, or pre-existing lung conditions

• May cause skin reactions, diarrhea, or liver enzyme elevation

• Not recommended during pregnancy or breastfeeding

• Avoid self-medicating with over-the-counter drugs that may interact with gefitinib

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects:

• Diarrhea and nausea

• Skin rash, dryness, or acne-like eruptions

• Fatigue and mild loss of appetite

Serious but rare side effects:

• Interstitial lung disease or severe pulmonary symptoms

• Liver toxicity or elevated liver enzymes

• Severe gastrointestinal reactions

Seek immediate medical attention if severe breathing difficulties, jaundice, or persistent diarrhea occurs.

Storage

• Store below 25°C in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Gefiren Tablet 250 mg is a targeted therapy for EGFR-mutated NSCLC, providing a precise, effective, and convenient oral treatment option for patients under careful oncologist supervision.