Dasaren Tablet 100 mg contains Dasatinib, a targeted anticancer medication classified as a tyrosine kinase inhibitor (TKI). It is primarily used in the treatment of certain types of leukemia, including chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) that are Philadelphia chromosome-positive (Ph+). Dasatinib works by blocking abnormal signals in cancer cells, inhibiting their growth and proliferation, and promoting cancer cell death.

Dasaren Tablet is an oral therapy that allows patients to manage their condition conveniently at home while under regular medical supervision. It is particularly effective in patients who are resistant or intolerant to previous therapies such as Imatinib.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Composition

Each tablet contains:

• Dasatinib 100 mg

Mechanism of Action

Dasatinib is a BCR-ABL tyrosine kinase inhibitor. It binds to the BCR-ABL protein produced by the Philadelphia chromosome mutation, preventing its activity. By inhibiting this abnormal protein, Dasatenib stops cancer cells from multiplying and induces apoptosis, effectively controlling leukemia progression. Dasatinib also inhibits other kinases involved in cancer cell growth.

Indications

Dasaren Tablet 100 mg is indicated for:

• Chronic, accelerated, or blast phase chronic myeloid leukemia (CML)

• Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)

• Patients resistant or intolerant to prior therapy with other TKIs such as Imatinib

• Treatment of certain cases of relapsed or refractory leukemia as determined by an oncologist

Dosage and Administration

• Adults: 100 mg orally once daily, or as prescribed by a healthcare professional.

• Take the tablet with water, with or without food.

• Swallow the tablet whole; do not crush or chew.

• Dosage may be adjusted based on response, tolerance, and side effects.

• Regular blood tests and monitoring for side effects are essential during therapy.

Precautions

• Use with caution in patients with liver or kidney impairment.

• Monitor for low blood cell counts (anemia, neutropenia, thrombocytopenia).

• May cause fluid retention, bleeding, or cardiac effects; report symptoms such as swelling, shortness of breath, or unusual bruising to your doctor.

• Avoid pregnancy during therapy; effective contraception is required for both males and females.

• Inform your doctor of any other medications to prevent drug interactions.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন.

Possible Side Effects

Common side effects may include:

• Low blood cell counts leading to anemia, infections, or bleeding

• Fatigue, headache, or dizziness

• Nausea, diarrhea, or vomiting

• Fluid retention, including swelling of ankles or around the eyes

• Shortness of breath or cough

Serious adverse effects may include heart problems, severe bleeding, or liver dysfunction. Immediate medical attention is required if these occur.

Storage

• Store below 25°C in a cool, dry place

• Protect from moisture and light

• Keep out of reach of children

Dasaren Tablet 100 mg is a powerful targeted therapy for managing Philadelphia chromosome-positive leukemias. When used under proper medical supervision, it helps control cancer progression, improves blood cell counts, and supports long-term patient outcomes.