Pirfedone Tablet 267 mg contains Pirfenidone, an antifibrotic and anti-inflammatory medication primarily used for the treatment of idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive lung disease characterized by scarring of lung tissue, leading to reduced lung function, shortness of breath, and decreased quality of life.

Pirfenidone works by inhibiting the synthesis of fibrotic proteins such as transforming growth factor-beta (TGF-β) and reducing inflammatory mediators that contribute to lung fibrosis. This helps slow disease progression, preserve lung function, and improve overall patient outcomes.

Pirfedone 267 mg provides a convenient oral dose for adults and is typically administered in a titrated schedule to achieve therapeutic levels while minimizing side effects. The tablet formulation ensures accurate dosing and ease of administration for long-term therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Key Features

• Contains Pirfenidone 267 mg per tablet

• Antifibrotic and anti-inflammatory agent for idiopathic pulmonary fibrosis

• Slows lung tissue scarring and preserves lung function

• Oral tablet for convenient long-term therapy

• Reduces disease progression and improves patient quality of life

• Suitable for use in combination with supportive care measures

Indications

Pirfedone Tablet 267 mg is indicated for:

• Idiopathic Pulmonary Fibrosis (IPF): Slows progression and preserves lung function

• Pulmonary fibrosis associated with other conditions: Only under specialist supervision

• Supportive therapy: Helps maintain exercise tolerance and quality of life in affected patients

Treatment should always be initiated and monitored by a pulmonologist or qualified healthcare professional.

Mechanism of Action

Pirfenidone exhibits both antifibrotic and anti-inflammatory effects:

• Inhibits TGF-β and collagen synthesis, reducing fibrotic tissue formation

• Suppresses inflammatory cytokines such as TNF-alpha and IL-1, decreasing inflammation-related tissue damage

• Protects lung tissue by slowing fibroblast proliferation and extracellular matrix deposition

These actions help slow the progression of pulmonary fibrosis, maintaining lung capacity and delaying the decline in respiratory function.

Dosage and Administration

• Standard dosing involves gradual titration to reach the recommended total daily dose

• Tablets are typically taken orally three times a day with food to reduce gastrointestinal discomfort

• Regular monitoring of liver function, kidney function, and lung status is recommended

• Dose adjustments may be required in patients with liver impairment, kidney impairment, or other comorbidities

• Adherence to prescribed dosing schedule is essential for optimal efficacy

Possible Side Effects

Common side effects:

• Nausea and vomiting

• Loss of appetite

• Fatigue and dizziness

• Rash or photosensitivity reactions

• Diarrhea or dyspepsia

Serious but rare side effects:

• Liver function abnormalities

• Severe skin reactions

• Allergic reactions

Patients should seek immediate medical attention if they experience persistent vomiting, jaundice, severe rash, or unusual swelling.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Use under the supervision of a pulmonologist or specialist

• Avoid direct sunlight or use protective measures to prevent photosensitivity reactions

• Regular monitoring of liver and kidney function is essential

• Inform the doctor about all medications to avoid potential drug interactions

• Not recommended during pregnancy or breastfeeding without medical supervision

Storage Instructions

• Store in a cool, dry place below 25°C

• Protect from light and moisture

• Keep tablets in the original container, tightly closed

• Keep out of reach of children.