Uticure Tablet 1 gm is a specialized urinary antiseptic medication used to prevent and manage urinary tract infections (UTIs). It is particularly effective in adult patients with recurrent or chronic infections of the urinary system. By maintaining a sterile environment in the urinary tract, Uticure helps reduce symptoms such as painful urination, urgency, frequency, and lower abdominal discomfort, promoting overall urinary health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Urinary Antiseptic

• Urinary Tract Infection Management

Indications

Uticure Tablet 1 gm is indicated for:

• Prevention and treatment of urinary tract infections (UTIs), especially in patients prone to recurrent infections

• Management of chronic bacteriuria in adults

• Supporting urinary tract health in post-surgical patients or individuals with structural abnormalities of the urinary system

Pharmacology / Mode of Action

Uticure contains Methenamine Hippurate, which acts as a urinary antiseptic. After oral administration, methenamine is excreted in the urine, where it is hydrolyzed in an acidic urinary environment to release formaldehyde. This formaldehyde acts as a broad-spectrum antibacterial agent, inhibiting the growth of Escherichia coli, Proteus, Klebsiella, and other uropathogens.

The drug works selectively in the urinary tract without significant systemic absorption, minimizing side effects while effectively sterilizing urine. Methenamine does not promote bacterial resistance, making it suitable for long-term prophylactic use in patients with recurring UTIs.

Dosage & Administration

• Adults: 1 gram twice daily with food to reduce gastrointestinal irritation

• Children: Safety and efficacy have not been well established in patients under 12 years of age

• Administration: Swallow tablets whole with a full glass of water. Adequate fluid intake is recommended to enhance urinary flow and drug efficacy

Contraindications

Uticure Tablet 1 gm should not be used in patients with:

• Severe renal impairment

• Urinary retention

• Hypersensitivity to methenamine or any component of the formulation

• Severe liver disease or metabolic disorders affecting urine acidity

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Generally well tolerated. Some patients may experience:

• Gastrointestinal disturbances: nausea, vomiting, mild abdominal discomfort

• Skin reactions: rash or urticaria (rare)

• Urine discoloration: harmless, may appear slightly brown or yellow

• Allergic reactions: extremely rare

Precautions & Warnings

• Monitor patients with renal impairment or those taking urinary alkalinizing agents, as effectiveness depends on acidic urine

• Use caution in patients with bladder outlet obstruction

• Long-term use should be monitored under medical supervision to avoid potential formaldehyde-related irritation

Pregnancy & Lactation

• Pregnancy: Use only if clearly needed; limited human data available

• Lactation: Safety not established; caution advised

Storage

• Store at room temperature (20–25°C), in a dry place, protected from light and moisture.