Pegalin ER Tablet 82.5 mg contains Pregabalin in an extended-release formulation designed to provide steady and controlled release of the medicine over time. It is used in the management of neuropathic pain, epilepsy, and generalized anxiety disorder. The ER formulation helps maintain consistent drug levels in the body, improving symptom control and reducing dosing frequency compared to immediate-release forms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Pregabalin 82.5 mg (Extended Release)

Indications

Pegalin ER Tablet is indicated for:

• Neuropathic pain (diabetic neuropathy, post-herpetic neuralgia)
• Fibromyalgia
• Adjunct therapy for partial seizures (epilepsy)
• Generalized anxiety disorder (GAD)
• Chronic nerve pain conditions requiring sustained therapy

Mechanism of Action

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This reduces the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P. The extended-release formulation ensures gradual absorption, maintaining stable plasma levels and providing continuous symptom relief throughout the day.

Dosage and Administration

• Usually taken once daily or as directed by a physician.
• Swallow whole with water; do not crush, chew, or break the tablet.
• Should be taken at the same time each day for consistent effect.
• Dosage is individualized based on condition and response.
• Do not stop suddenly without medical supervision.

Benefits

• Long-lasting, steady pain relief
• Reduced dosing frequency (once daily convenience)
• Effective control of neuropathic pain symptoms
• Improves sleep quality and daily functioning
• Helps manage anxiety and seizure disorders

Side Effects

Pegalin ER Tablet may cause:

• Drowsiness or dizziness
• Blurred vision
• Weight gain
• Dry mouth
• Fatigue
• Peripheral edema (rare)

Most side effects are mild and improve with continued use.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• May cause dizziness; avoid driving or operating machinery.
• Use with caution in patients with kidney impairment (dose adjustment required).
• Do not crush or split the tablet due to extended-release formulation.
• Avoid alcohol during treatment.
• Do not discontinue abruptly; tapering may be required.
• Use only under medical supervision.

Storage

• Store below 30°C
• Protect from moisture and light
• Keep out of reach of children.