Pazonib Tablet 200 mg contains Pazopanib Hydrochloride, an oral targeted anticancer medication classified as a tyrosine kinase inhibitor (TKI). It is used in the treatment of certain advanced cancers by inhibiting multiple receptor tyrosine kinases involved in tumor growth and angiogenesis (formation of new blood vessels that supply tumors). By blocking these pathways, Pazonib helps slow cancer progression and reduce tumor spread.

Pazopanib works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, and VEGFR-3), platelet-derived growth factor receptors (PDGFR), and c-Kit. These receptors play a crucial role in tumor angiogenesis and cell proliferation. By targeting these signaling pathways, Pazonib disrupts the blood supply to tumors and inhibits cancer cell growth, making it an effective therapy for specific malignancies.

Pazonib Tablet 200 mg is administered orally and is prescribed under the supervision of an experienced oncologist.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Pazonib Tablet 200 mg is indicated for the treatment of:

• Advanced renal cell carcinoma (kidney cancer)

• Advanced soft tissue sarcoma (after prior chemotherapy)

Treatment suitability depends on clinical evaluation and oncologist recommendation.

Dosage and Administration

• The usual recommended dose is 800 mg once daily (four 200 mg tablets), or as prescribed by the physician.

• Tablets should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.

• Swallow tablets whole with water; do not crush or break them.

• Take the dose at the same time each day.

Dose adjustments may be necessary based on patient tolerance, liver function, or side effects. Regular monitoring is essential during treatment.

Benefits of Pazonib Tablet 200 mg

• Targeted therapy that inhibits tumor blood vessel formation

• Helps delay disease progression

• Oral administration for convenient outpatient treatment

• Proven clinical efficacy in renal cell carcinoma and soft tissue sarcoma

• Reduces reliance on traditional cytotoxic chemotherapy

Possible Side Effects

Common side effects may include:

• Hypertension (high blood pressure)

• Diarrhea

• Nausea or vomiting

• Fatigue

• Hair color changes

• Loss of appetite

Serious side effects may include liver toxicity, heart rhythm abnormalities, bleeding, or thrombotic events. Routine monitoring of blood pressure and liver function tests is recommended during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Liver function should be assessed before and during treatment.

• Use cautiously in patients with a history of cardiovascular disease.

• Avoid strong CYP3A4 inhibitors or inducers unless advised by a healthcare professional.

• Not recommended during pregnancy or breastfeeding due to potential fetal harm.

• Effective contraception should be used during treatment.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Pazonib Tablet 200 mg offers a modern, targeted treatment approach for advanced cancers, helping manage disease progression with an evidence-based mechanism under specialized medical supervision.