Arsenor Tablet 30 mg (Apremilast)

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Arsenor Tablet 30 mg contains Apremilast, an oral phosphodiesterase-4 (PDE4) inhibitor used in the treatment of inflammatory autoimmune conditions. It works by modulating the immune response and reducing the production of inflammatory mediators. Arsenor is commonly prescribed for chronic plaque psoriasis, psoriatic arthritis, and related inflammatory disorders.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

  • Active Ingredient: Apremilast 30 mg per tablet

Mechanism of Action

Apremilast selectively inhibits phosphodiesterase-4 (PDE4), an enzyme involved in inflammatory signaling pathways. By blocking PDE4, it increases intracellular cyclic adenosine monophosphate (cAMP) levels, leading to a reduction in pro-inflammatory cytokines such as TNF-alpha, IL-17, and IL-23. This helps control inflammation and improves symptoms of autoimmune diseases.


Indications

Arsenor Tablet is indicated for:

  • Moderate to severe plaque psoriasis
  • Active psoriatic arthritis
  • Oral ulcers associated with Behçet’s disease (in some cases)
  • Chronic inflammatory skin conditions (as prescribed by a physician)

Dosage and Administration

  • Initial dose is usually titrated over several days to reduce gastrointestinal side effects
  • Maintenance dose: 30 mg twice daily or as prescribed by a physician
  • Can be taken with or without food
  • Tablets should be swallowed whole with water
  • Dose adjustment may be required in patients with renal impairment

Benefits

  • Reduces skin inflammation and scaling in psoriasis
  • Improves joint pain, swelling, and stiffness in psoriatic arthritis
  • Oral therapy avoids injectable treatment
  • Long-term disease control in chronic inflammatory conditions
  • Does not require routine laboratory monitoring in most patients

Possible Side Effects

Common side effects may include:

  • Diarrhea
  • Nausea or vomiting
  • Headache
  • Weight loss
  • Upper respiratory tract infections

Less common but serious side effects:

  • Severe depression or mood changes
  • Significant weight reduction
  • Hypersensitivity reactions

Patients should report any persistent or severe symptoms to a healthcare provider.


Precautions and Warnings

  • Use cautiously in patients with a history of depression or psychiatric disorders
  • Monitor body weight during long-term therapy
  • Dose adjustment may be required in severe renal impairment
  • Not recommended during pregnancy unless clearly necessary
  • Use under medical supervision for chronic autoimmune conditions

Drug Interactions

  • May interact with strong enzyme inducers such as rifampicin, phenytoin, or carbamazepine, reducing effectiveness
  • Inform physician about all current medications
  • No significant interactions with most common NSAIDs or biologics

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

  • Store below 30°C
  • Protect from moisture and light
  • Keep out of reach of children

Conclusion

Arsenor Tablet 30 mg (Apremilast) is an effective oral therapy for managing chronic inflammatory conditions such as psoriasis and psoriatic arthritis. By targeting key inflammatory pathways, it helps improve skin and joint symptoms while offering convenient long-term disease control under medical supervision.

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Arsenor Tablet 30 mg (Apremilast)
Arsenor Tablet 30 mg (Apremilast)
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