Olmevas AM Tablet 5 mg+20 mg is a combination antihypertensive medicine containing Amlodipine Besilate, a calcium channel blocker, and Olmesartan Medoxomil, an angiotensin II receptor blocker (ARB). This dual-action formulation is used for the effective management of high blood pressure (hypertension), especially in patients who require combination therapy for better blood pressure control. It helps reduce the risk of cardiovascular complications such as stroke, heart attack, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Amlodipine Besilate equivalent to Amlodipine 5 mg
• Olmesartan Medoxomil 20 mg

Mechanism of Action

Amlodipine works by relaxing and widening blood vessels through inhibition of calcium ion entry into vascular smooth muscle cells, leading to reduced peripheral resistance.

Olmesartan Medoxomil blocks angiotensin II receptors (AT1), preventing vasoconstriction and aldosterone release, which further lowers blood pressure.

Together, these two agents provide complementary blood pressure reduction through different mechanisms, resulting in improved efficacy and smoother 24-hour control.

Indications

Olmevas AM Tablet is indicated for:

• Essential hypertension (high blood pressure)
• Patients not adequately controlled on monotherapy
• Combination therapy for moderate to severe hypertension
• Reduction of cardiovascular risk in hypertensive patients

Dosage and Administration

• Take exactly as prescribed by a healthcare professional.
• Usually taken once daily at the same time each day.
• Can be taken with or without food.
• Swallow the tablet whole with water.
• Do not discontinue without medical advice.

Benefits

• Provides dual mechanism blood pressure control
• Helps maintain stable 24-hour BP levels
• Reduces risk of heart attack and stroke
• Effective in patients not responding to single therapy
• Convenient once-daily dosing improves adherence

Side Effects

Common side effects may include:

• Dizziness
• Headache
• Swelling of ankles or feet (due to amlodipine)
• Fatigue
• Flushing

Serious but rare side effects:

• Excessively low blood pressure
• Kidney function impairment
• High potassium levels (hyperkalemia)
• Severe allergic reactions or swelling (angioedema)

Seek medical attention if serious symptoms occur.

Precautions and Warnings

• Not recommended during pregnancy due to risk to the fetus.
• Use cautiously in patients with liver, kidney, or heart conditions.
• Monitor blood pressure regularly during therapy.
• Avoid potassium supplements unless prescribed.
• May cause dizziness; caution while driving or operating machinery.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Olmevas AM Tablet may interact with:

• Other antihypertensive drugs
• Diuretics (water pills)
• Potassium supplements or potassium-sparing agents
• NSAIDs (may reduce antihypertensive effect)
• Lithium (risk of toxicity)

Always inform your healthcare provider about all medicines being taken.

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.