Telisa Plus Tablet 40 mg+12.5 mg is a combination antihypertensive medication containing Telmisartan 40 mg, an angiotensin II receptor blocker (ARB), and Hydrochlorothiazide 12.5 mg, a thiazide diuretic. This synergistic combination is designed to provide effective blood pressure control in patients who require more than one agent to achieve target blood pressure.

Telmisartan works by relaxing blood vessels and reducing resistance, while Hydrochlorothiazide helps eliminate excess salt and water through the kidneys, lowering blood volume. Together, they offer a dual mechanism to manage hypertension effectively. Telisa Plus Tablet 40 mg+12.5 mg is suitable for once-daily dosing, making it convenient for long-term therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Telisa Plus Tablet 40 mg+12.5 mg is indicated for:

• Essential hypertension in adults when monotherapy with an ARB or diuretic is insufficient

• Patients requiring combination therapy to reach and maintain target blood pressure

• Cardiovascular risk reduction in hypertensive patients, including prevention of stroke, heart attack, and vascular complications

• Can be used for long-term management of hypertension to prevent kidney damage and reduce cardiovascular strain

It is not intended for acute hypertensive emergencies but for ongoing control of blood pressure and cardiovascular protection.

Mechanism of Action

Telisa Plus Tablet combines two complementary mechanisms:

• Telmisartan (ARB): Blocks angiotensin II from binding to AT1 receptors in blood vessels, leading to vasodilation, reduced aldosterone secretion, and lower blood pressure

• Hydrochlorothiazide (Thiazide Diuretic): Increases excretion of sodium and water by the kidneys, reducing blood volume and peripheral resistance

• Combined effect: Enhanced blood pressure reduction compared to either component alone, with additional cardiovascular and renal protective benefits

This dual action ensures effective, long-term management of hypertension, particularly in patients who do not achieve adequate control with a single agent.

Dosage and Administration

• The usual adult dose is one tablet orally once daily, with or without food

• Tablets should be swallowed whole with water

• Dose adjustment may be required for patients with renal or hepatic impairment

• Consistent daily use is essential for maintaining blood pressure within the target range

• Regular monitoring of blood pressure, kidney function, and electrolytes, especially potassium and sodium, is recommended

Precautions and Warnings

• Avoid use during second and third trimesters of pregnancy due to risk of fetal harm

• Monitor patients with kidney disease, liver impairment, or electrolyte imbalances

• Hydrochlorothiazide may increase sensitivity to sunlight; use sun protection if exposed

• May cause dizziness, especially during initial therapy or dose adjustments; avoid driving or operating machinery until effects are known

• Inform your healthcare provider about all medications, including NSAIDs, other diuretics, or potassium supplements, to prevent interactions

Side Effects

Telisa Plus Tablet 40 mg+12.5 mg is generally well tolerated. Common side effects may include:

• Dizziness or lightheadedness

• Headache or fatigue

• Mild gastrointestinal symptoms such as nausea

• Electrolyte disturbances, including low sodium or potassium imbalance

• Rare side effects: hypotension, kidney function changes, allergic reactions, or swelling

Seek medical attention if severe dizziness, swelling, shortness of breath, or other unusual symptoms occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

Store below 30°C in a cool, dry place, protected from light and moisture. Keep out of reach of children.

Telisa Plus Tablet 40 mg+12.5 mg provides effective once-daily blood pressure control through dual mechanisms, offering enhanced cardiovascular and renal protection for patients requiring combination therapy.