Olapar Tablet 150 mg contains Olaparib, an oral targeted anticancer medicine belonging to the PARP inhibitor class. It is used in the treatment and maintenance therapy of certain cancers associated with BRCA gene mutations and other defects in DNA repair pathways. By targeting cancer cell repair mechanisms, Olaparib helps slow disease progression and improve treatment outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Olaparib
• Strength: 150 mg per tablet

Mechanism of Action

Olaparib works by inhibiting poly ADP-ribose polymerase (PARP) enzymes, which are essential for repairing damaged DNA in cells. Cancer cells with BRCA1 or BRCA2 mutations depend heavily on PARP-mediated repair to survive. Blocking PARP leads to accumulation of DNA damage in these cancer cells, ultimately resulting in cell death while sparing most normal cells.

Indications

Olapar Tablet 150 mg is indicated for:

• Maintenance treatment of advanced ovarian cancer
• HER2-negative breast cancer with BRCA mutation
• Pancreatic cancer with germline BRCA mutation (selected cases)
• Metastatic prostate cancer with DNA repair gene mutations
• Other oncology indications as prescribed by a specialist

Dosage and Administration

• Taken orally under the supervision of an oncologist
• Dosage depends on cancer type, body condition, and treatment protocol
• Usually taken twice daily or as directed by a physician
• Tablets should be swallowed whole with water
• May be taken with or without food

Benefits

• Targets cancer cells with specific genetic mutations
• Helps delay disease progression and recurrence
• Oral therapy offers convenience for long-term treatment
• Improves progression-free survival in eligible patients

Possible Side Effects

Common side effects may include:

• Nausea and vomiting
• Fatigue or weakness
• Anemia (low hemoglobin)
• Decreased appetite
• Diarrhea
• Headache

Serious adverse effects may include bone marrow suppression and rare secondary malignancies. Regular monitoring is required during therapy.

Precautions and Warnings

• Must be used only under oncology specialist supervision
• Regular blood tests (CBC and liver function) are required
• Not recommended during pregnancy or breastfeeding
• Use with caution in patients with liver or kidney impairment
• Inform your doctor about all ongoing medications and medical history

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Olapar Tablet 150 mg (Olaparib) is an advanced targeted cancer therapy used in BRCA-mutated and other specific cancers. It works by blocking DNA repair in cancer cells, helping to control disease progression when used under strict medical supervision.