Evo 250 mg Tablet is a broad-spectrum, third-generation fluoroquinolone antibiotic from the therapeutic class of 4-Quinolone preparations. It is formulated to treat a variety of bacterial infections in adults by providing effective coverage against both Gram-positive and Gram-negative organisms. Evo 250 mg is commonly prescribed for mild to moderate infections affecting the respiratory tract, urinary tract, skin, and prostate.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Evo 250 mg is indicated for the treatment of the following infections in adults (18 years of age and above):

• Respiratory tract infections, including:

  • Acute bacterial sinusitis

  • Acute exacerbation of chronic bronchitis

  • Community-acquired pneumonia

  • Nosocomial (hospital-acquired) pneumonia

• Uncomplicated and complicated skin and soft tissue infections

• Chronic bacterial prostatitis

• Uncomplicated and complicated urinary tract infections (mild to moderate)

Pharmacology

Evo 250 mg is a synthetic, chiral fluorinated carboxyquinolone antibiotic. It exerts its antibacterial action by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, transcription, repair, and recombination. By blocking these enzymes, Evo 250 mg prevents bacterial cell division and leads to bacterial cell death. It has demonstrated strong in-vitro activity against a wide range of Gram-positive and Gram-negative microorganisms.

Dosage and Administration

Dosage depends on the type and severity of infection:

• Acute sinusitis: 500 mg once daily for 10–14 days

• Acute exacerbation of chronic bronchitis: 250–500 mg once daily for 7–10 days

• Community-acquired pneumonia: 500 mg once or twice daily for 7–14 days

• Nosocomial pneumonia: 750 mg once daily for 7–14 days

• Skin and soft tissue infections: 500 mg once or twice daily for 7–14 days

• Chronic bacterial prostatitis: 500 mg once daily for 28 days

• Urinary tract infections:

  • 250 mg once daily for 7–10 days

  • 250 mg once daily for 3 days in uncomplicated infections

Dose adjustment is required in patients with impaired renal function.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Antacids, iron preparations, and adsorbents may reduce the absorption of Evo 250 mg

• Concomitant use with NSAIDs may increase the risk of central nervous system stimulation

• Warfarin may increase the risk of bleeding when used with Evo 250 mg

Contraindications

Evo 250 mg is contraindicated in patients with known hypersensitivity to fluoroquinolone antibiotics or any component of this formulation.

Side Effects

Evo 250 mg is generally well tolerated. Common side effects include:

• Nausea

• Vomiting

• Diarrhea

• Abdominal pain

• Flatulence

Rarely, phototoxic reactions may occur. Very rare adverse effects include tremors, anxiety, depression, confusion, and other central nervous system effects.

Pregnancy and Lactation

Evo 250 mg is classified as US FDA pregnancy category C. It should be avoided during pregnancy and lactation unless the potential benefit outweighs the possible risk to the fetus or infant.

Precautions and Warnings

• Adequate fluid intake should be maintained during treatment

• Caution is advised in patients with renal impairment

• Prolonged or inappropriate use may increase the risk of adverse effects

Storage Conditions

Store in a dry place away from light and heat. Keep out of reach of children.