Eburic Tablet 40 mg contains Febuxostat, a selective xanthine oxidase inhibitor used for the long-term management of hyperuricemia associated with gout. It effectively lowers elevated serum uric acid levels, helping to prevent gout flares and reduce the formation of urate crystals in joints and tissues. Eburic Tablet is suitable for patients who are unable to tolerate or do not respond adequately to other uric acid–lowering therapies.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Febuxostat 40 mg

Therapeutic Class

Xanthine oxidase inhibitor
Antigout agent

Pharmacology

Febuxostat works by selectively inhibiting xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine and xanthine into uric acid. By reducing uric acid production, febuxostat effectively lowers serum urate concentrations without affecting other enzymes involved in purine and pyrimidine metabolism.

Unlike some traditional therapies, febuxostat is primarily metabolized in the liver and can be used in patients with mild to moderate renal impairment under medical supervision. Regular use helps dissolve existing urate deposits and prevents the formation of new crystals, thereby reducing the frequency and severity of gout attacks over time.

Indications

Eburic Tablet 40 mg is indicated for:

• Chronic hyperuricemia in patients with gout

• Prevention of gout flares

• Management of uric acid overproduction

It is not intended for the treatment of acute gout attacks but helps in long-term disease control.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

• The usual recommended starting dose is 40 mg once daily.

• Dose may be adjusted based on serum uric acid levels and clinical response.

Eburic Tablet can be taken with or without food. Adequate hydration is recommended during therapy. Dose adjustments should be made by a healthcare professional.

Contraindications

Eburic Tablet is contraindicated in patients with:

• Known hypersensitivity to febuxostat

• Concomitant use of azathioprine or mercaptopurine due to risk of severe toxicity

Precautions and Warnings

• Gout flares may occur during the initial phase of uric acid–lowering therapy; prophylactic treatment may be recommended.

• Caution is advised in patients with a history of cardiovascular disease.

• Liver function tests should be monitored periodically.

• Not recommended for use in asymptomatic hyperuricemia.

Side Effects

Commonly reported side effects include:

• Liver enzyme elevation

• Nausea

• Joint pain or gout flare during initiation

• Rash

• Headache

Most adverse effects are mild to moderate in severity.

Use in Special Populations

• Pregnancy: Use only if clearly necessary and prescribed by a physician.

• Lactation: Caution is advised; consult a healthcare professional.

• Renal impairment: Can be used in mild to moderate cases with monitoring.

Storage

Store in a cool and dry place below 30°C. Protect from light and moisture. Keep out of reach of children.