Ivaten Tablet 7.5 mg contains Ivabradine, a selective heart rate-lowering agent used primarily for the management of chronic stable angina and heart failure with reduced ejection fraction. Ivabradine acts on the sinoatrial (SA) node, the natural pacemaker of the heart, to reduce heart rate without affecting myocardial contractility or blood pressure. This unique mechanism makes it an effective treatment option for patients who cannot tolerate beta-blockers or require additional heart rate control.

By lowering the heart rate, Ivaten Tablet reduces myocardial oxygen demand, decreases the frequency of angina attacks, and improves exercise tolerance in patients with chronic stable angina. In heart failure, slowing the heart rate allows the ventricles to fill more effectively, enhancing cardiac efficiency and reducing symptoms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Ivaten Tablet 7.5 mg is indicated for:

• Chronic stable angina pectoris in patients with normal sinus rhythm

• Heart failure with reduced ejection fraction (HFrEF) in patients with elevated heart rate

• Management of patients intolerant to or inadequately controlled by beta-blockers

It may be used alone or in combination with other heart medications as prescribed by a physician.

Mechanism of Action

Ivabradine selectively inhibits the funny current (If) in the sinoatrial node. This current regulates spontaneous pacemaker activity in the heart. By inhibiting the If current, Ivabradine slows the heart rate without altering myocardial contractility, conduction, or ventricular repolarization.

Unlike beta-blockers or calcium channel blockers, Ivabradine does not reduce blood pressure or exert negative inotropic effects, making it particularly beneficial in patients with low blood pressure or compromised cardiac function.

Dosage and Administration

• The usual starting dose is 5 mg twice daily, which may be increased to 7.5 mg twice daily based on patient response and heart rate.

• Take the tablet orally with water, preferably at the same times each day.

• Swallow the tablet whole; do not crush or chew.

• Regular monitoring of heart rate and clinical response is recommended.

The dose may need adjustment in elderly patients or those with liver impairment.

Precautions

Before taking Ivaten Tablet, inform your doctor if you have:

• Severe bradycardia (heart rate <50 bpm)

• Sick sinus syndrome or sinoatrial block

• Atrial fibrillation or other arrhythmias

• Severe hypotension or unstable angina

• Liver impairment

Patients should avoid sudden discontinuation and follow regular heart rate and blood pressure monitoring.

Use in Pregnancy and Lactation

Ivabradine should be used during pregnancy only if clearly needed and prescribed by a physician. It is not recommended during breastfeeding due to limited safety data.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Bradycardia (slow heart rate)

• Dizziness or fatigue

• Visual disturbances (phosphenes)

• Headache

• Nausea

Serious but rare side effects may include atrial fibrillation or severe symptomatic bradycardia. Immediate medical attention is necessary if severe symptoms occur.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Ivaten Tablet 7.5 mg provides targeted heart rate reduction for effective management of angina and heart failure, improving quality of life when used under medical supervision.