Sinjard-M Tablet 5 mg+500 mg is a combination oral antidiabetic medicine containing Empagliflozin and Metformin Hydrochloride. It is used for the management of type 2 diabetes mellitus when blood glucose levels are not adequately controlled with diet, exercise, or single-drug therapy. This dual-action formulation helps improve glycemic control through complementary mechanisms, making it an effective option for long-term diabetes management.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Empagliflozin 5 mg
• Metformin Hydrochloride 500 mg

Mechanism of Action

Sinjard-M Tablet works through two different pathways to lower blood glucose levels:

• Empagliflozin: An SGLT2 inhibitor that reduces glucose reabsorption in the kidneys, leading to increased urinary glucose excretion and improved blood sugar control.
• Metformin Hydrochloride: A biguanide that decreases hepatic glucose production, reduces intestinal glucose absorption, and improves insulin sensitivity in peripheral tissues.

Together, these actions provide enhanced and sustained glycemic control.

Indications

Sinjard-M Tablet is indicated for:

• Management of type 2 diabetes mellitus in adults
• Patients inadequately controlled on metformin or other antidiabetic therapy alone
• Combination therapy to improve glycemic control alongside diet and exercise

Dosage and Administration

• The dosage should be taken as prescribed by a physician.
• Usually taken once or twice daily depending on clinical condition.
• It is recommended to take the tablet with meals to reduce gastrointestinal discomfort.
• Regular monitoring of blood glucose levels is advised during treatment.

Benefits

• Dual mechanism for improved blood sugar control
• Helps reduce fasting and post-meal glucose levels
• Supports weight management (Empagliflozin component)
• Improves insulin sensitivity (Metformin component)
• May offer cardiovascular and renal benefits in diabetic patients

Side Effects

Common side effects may include:

• Nausea or vomiting
• Diarrhea
• Abdominal discomfort
• Increased urination
• Genital or urinary tract infections

Rare but serious side effects include lactic acidosis (from Metformin), ketoacidosis, or severe dehydration. Immediate medical attention is required if severe symptoms occur.

Precautions and Warnings

• Not recommended for type 1 diabetes or diabetic ketoacidosis.
• Use cautiously in patients with kidney or liver impairment.
• Avoid excessive alcohol intake due to increased risk of lactic acidosis.
• Monitor renal function and blood glucose regularly.
• Inform your doctor if you are pregnant or breastfeeding.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Sinjard-M Tablet may interact with:

• Diuretics (increased risk of dehydration)
• Insulin or other antidiabetic drugs (risk of hypoglycemia)
• Alcohol (increased risk of lactic acidosis)
• Certain blood pressure medications

Always consult a healthcare professional before combining with other medicines.

Storage

• Store below 30°C in a dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children.