Choliva Tablet 10 mg contains Obeticholic Acid, a potent medication primarily used for the treatment of liver disorders, particularly primary biliary cholangitis (PBC). PBC is a chronic condition in which the bile ducts in the liver are gradually damaged, leading to bile accumulation, liver inflammation, and potential liver damage over time. Choliva helps improve liver function by regulating bile acid metabolism and reducing liver inflammation.

Obeticholic Acid, the active ingredient in Choliva, is a selective farnesoid X receptor (FXR) agonist. By activating FXR, it helps control bile acid production and transport, protecting liver cells from the toxic effects of bile accumulation. This mechanism makes Choliva an essential treatment option for patients with PBC, particularly those who do not respond adequately to standard therapy such as ursodeoxycholic acid (UDCA).

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

How Choliva Works

Choliva Tablet works by:

• Activating the farnesoid X receptor (FXR) in the liver and intestines

• Reducing the synthesis of bile acids, preventing accumulation in liver cells

• Enhancing bile acid transport and promoting excretion

• Decreasing liver inflammation and fibrosis over time

By targeting the underlying mechanisms of bile acid dysregulation, Choliva supports liver function and helps prevent progression of liver damage associated with PBC.

Indications

Choliva Tablet 10 mg is indicated for:

• Primary biliary cholangitis (PBC) in adults

• Patients with inadequate response or intolerance to ursodeoxycholic acid (UDCA)

• Management of liver function abnormalities related to bile acid accumulation

It is prescribed as part of a comprehensive management plan under the supervision of a hepatologist or gastroenterologist.

Dosage and Administration

The dosage of Choliva Tablet should be individualized based on the patient’s condition and response to therapy. Typical recommendations include:

• Usually taken once daily with food to improve absorption

• Initial dosing may start at 5 mg daily and can be increased to 10 mg based on tolerance and liver function tests

• Regular monitoring of liver enzymes and bilirubin levels is essential during therapy

• Patients should not adjust the dose without consulting their physician

Compliance with the prescribed regimen is critical for optimal liver protection and disease management.

Precautions and Warnings

Before taking Choliva Tablet, patients should inform their healthcare provider if they have:

• Severe liver impairment or decompensated liver disease

• History of liver transplantation

• High cholesterol or triglyceride levels

• Gallbladder disease

Choliva may cause pruritus (itching), and patients should report any persistent or severe symptoms. Use during pregnancy and breastfeeding should only be considered if the benefits outweigh the risks.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Itching (pruritus)

• Fatigue

• Abdominal discomfort or pain

• Nausea

• Joint pain

Serious side effects are rare but may include liver decompensation or severe allergic reactions. Immediate medical attention is necessary if severe symptoms occur.

Storage Instructions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Choliva Tablet 10 mg provides a reliable and clinically proven option for managing primary biliary cholangitis, supporting liver function, and improving quality of life in patients with chronic liver disease.