Glipxen Tablet 5 mg contains Linagliptin, an oral antidiabetic medication belonging to the class of dipeptidyl peptidase-4 (DPP-4) inhibitors. It is used to improve glycemic control in adults with type 2 diabetes mellitus. Linagliptin helps regulate blood sugar levels by enhancing the body’s natural incretin system, leading to better insulin release and reduced glucose production.

This medicine is commonly used alone or in combination with other antidiabetic agents such as metformin.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Linagliptin 5 mg

Mechanism of Action

Linagliptin works by inhibiting the DPP-4 enzyme, which breaks down incretin hormones such as GLP-1 and GIP. By preventing their degradation, it increases insulin secretion in response to meals and reduces glucagon release from the pancreas. This results in improved blood glucose control without causing significant hypoglycemia when used alone.

Indications

Glipxen Tablet 5 mg is indicated for:

• Type 2 diabetes mellitus in adults
• As monotherapy when diet and exercise are insufficient
• Combination therapy with metformin, sulfonylureas, or insulin
• Patients requiring improved postprandial and fasting glucose control

Dosage and Administration

• Taken orally once daily as prescribed by a physician
• Can be taken with or without food
• No dose adjustment is usually required in renal or hepatic impairment
• Should be used along with diet and exercise for best results
• Regular monitoring of blood glucose levels is recommended

Contraindications

Glipxen Tablet should not be used in:

• Known hypersensitivity to Linagliptin or any excipients
• Type 1 diabetes mellitus
• Diabetic ketoacidosis

Side Effects

Possible side effects include:

• Nasopharyngitis (cold-like symptoms)
• Headache
• Cough
• Mild gastrointestinal discomfort
• Hypoglycemia (mainly when combined with insulin or sulfonylureas)
• Rare allergic skin reactions or pancreatitis

Precautions

• Monitor blood glucose regularly during therapy
• Use cautiously in patients with history of pancreatitis
• Adjust other antidiabetic medications to avoid hypoglycemia
• Maintain healthy diet and physical activity
• Discontinue if severe abdominal pain or allergic reactions occur

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Glipxen Tablet may interact with:

• Sulfonylureas and insulin (increased risk of hypoglycemia)
• Rifampicin (may reduce effectiveness)
• Other antidiabetic medications
• Drugs affecting hepatic enzyme activity

Storage Conditions

• Store below 30°C in a dry place
• Protect from moisture and direct sunlight
• Keep out of reach of children.