Evania M Tablet 12.5 mg + 1000 mg is a fixed-dose combination oral antidiabetic medicine containing Empagliflozin and Metformin Hydrochloride. It is widely used in the treatment of type 2 diabetes mellitus, especially in patients who require combination therapy to achieve adequate glycemic control.

This formulation combines a moderate-to-high dose of both agents, offering effective control of blood sugar levels through complementary mechanisms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Empagliflozin 12.5 mg
• Metformin Hydrochloride 1000 mg

For oral use.

Mechanism of Action

Evania M works via dual pathways:

Empagliflozin (SGLT2 inhibitor)

• Inhibits glucose reabsorption in the kidneys
• Increases urinary glucose excretion
• Reduces blood glucose levels independent of insulin
• May aid in weight loss and reduce blood pressure

Metformin (Biguanide)

• Decreases glucose production in the liver
• Improves insulin sensitivity in peripheral tissues
• Reduces intestinal glucose absorption

Together, they provide improved control of both fasting and postprandial blood glucose.

Indications

Evania M Tablet is indicated for:

• Type 2 Diabetes Mellitus
• Patients inadequately controlled with monotherapy
• Combination therapy alongside diet and exercise

Dosage and Administration

• Typically taken once or twice daily with meals
• Taking with food helps reduce gastrointestinal side effects of metformin
• Dosage should be individualized by a healthcare professional
• Tablets should be swallowed whole with water
• Not recommended for type 1 diabetes or diabetic ketoacidosis

Benefits

Evania M Tablet offers several advantages:

• Effective dual-action blood glucose control
• Reduces fasting and post-meal glucose levels
• Supports modest weight loss
• Low risk of hypoglycemia when used alone
• May provide cardiovascular and renal benefits
• Reduces pill burden with combination therapy

Possible Side Effects

Common side effects include:

• Nausea, diarrhea, abdominal discomfort
• Increased urination
• Urinary tract infections
• Genital fungal infections

Less common side effects:

• Dizziness
• Weakness
• Vitamin B12 deficiency with long-term use

Serious side effects:

• Lactic Acidosis
• Diabetic Ketoacidosis
• Kidney impairment

Precautions

• Always take with meals to minimize stomach upset
• Maintain adequate hydration
• Monitor kidney function regularly
• Avoid excessive alcohol intake
• Use cautiously in elderly patients
• Discontinue temporarily before surgery or contrast imaging

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Evania M may interact with:

• Diuretics (risk of dehydration)
• Insulin or sulfonylureas (risk of hypoglycemia)
• Alcohol (increased risk of lactic acidosis)
• Iodinated contrast agents

Storage

Store in a cool, dry place below 30°C, protected from light and moisture. Keep out of reach of children.