Don-A Suspension 5 mg/5 ml contains Domperidone Maleate, a selective dopamine D2 receptor antagonist formulated as an oral suspension for pediatric and adult patients. This liquid formulation is designed to relieve nausea, vomiting, and delayed gastric emptying, offering accurate dosing and ease of administration. Don-A Suspension is particularly useful for patients who have difficulty swallowing tablets or capsules, including children, elderly individuals, and those with gastrointestinal conditions.

Domperidone works by enhancing gastrointestinal motility, promoting the movement of food through the stomach and intestines, and thereby reducing symptoms of nausea, vomiting, and bloating. Its selective peripheral action minimizes central nervous system side effects, making it a well-tolerated option for both children and adults.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Domperidone Maleate: 5 mg per 5 ml

Indications

Don-A Suspension 5 mg/5 ml is indicated for:

• Relief of nausea and vomiting in pediatric and adult patients

• Management of gastroesophageal reflux (GER) symptoms such as regurgitation or vomiting

• Treatment of delayed gastric emptying and related digestive discomfort

• Supportive therapy for vomiting associated with infections, migraine, or medications

• Patients requiring oral liquid formulations for accurate and convenient dosing

Mechanism of Action

Domperidone acts by blocking dopamine D2 receptors in the gastrointestinal tract and chemoreceptor trigger zone (CTZ). Its primary effects include:

• Enhanced gastric motility, accelerating gastric emptying

• Reduction of nausea and vomiting by inhibiting signals from the CTZ

• Improved tolerance of oral feeding in patients with gastrointestinal disturbances

Because Domperidone has minimal penetration into the central nervous system, it avoids the sedative and neurological side effects commonly associated with other antiemetics.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The recommended dose varies by age, weight, and clinical condition. Typically, 5 ml of suspension (equivalent to 5 mg Domperidone) is administered 2–3 times daily, 15–30 minutes before meals. The dose may be adjusted for infants, children, or adults based on medical advice. The suspension should be shaken well before each use to ensure uniform distribution of the active ingredient.

Benefits of Don-A Suspension 5 mg/5 ml

• Safe and effective for pediatric and adult patients

• Provides relief from nausea, vomiting, and gastric discomfort

• Improves gastric motility and digestive function

• Liquid formulation ensures accurate and convenient dosing

• Minimizes central nervous system side effects

• Suitable for patients with swallowing difficulties

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Not recommended for children under 1 year unless prescribed

• Caution in patients with heart rhythm disorders, liver disease, or renal impairment

• Monitor for potential side effects such as abdominal cramps, diarrhea, headache, or dizziness

• Avoid concomitant use with medications that prolong the QT interval

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

• Shake well before each use

Pharmaceutical Category

Gastrointestinal Prokinetic / Antiemetic.