Don-A Pediatric Drop 5 mg/ml contains Domperidone Maleate, a dopamine D2 receptor antagonist, specifically formulated for pediatric use to manage gastrointestinal disturbances such as nausea, vomiting, and delayed gastric emptying. This oral liquid formulation allows precise dosing for infants and children, ensuring safety, ease of administration, and effective symptom control.

Domperidone works by enhancing gastrointestinal motility and increasing the movement of food through the stomach and intestines, thereby alleviating symptoms of nausea and vomiting. Unlike some other antiemetics, Domperidone does not significantly affect the central nervous system because it poorly crosses the blood-brain barrier, making it suitable and well-tolerated in children.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Domperidone Maleate: 5 mg per ml

Indications

Don-A Pediatric Drop 5 mg/ml is indicated for:

• Relief of nausea and vomiting in children

• Management of gastroesophageal reflux (GER) symptoms, such as regurgitation or vomiting

• Supportive treatment in delayed gastric emptying

• Prevention of vomiting associated with migraine, infection, or medication use

• Pediatric patients requiring oral liquid formulations for accurate dosing

Mechanism of Action

Domperidone exerts its effect by blocking dopamine D2 receptors in the gastrointestinal tract and chemoreceptor trigger zone (CTZ). This leads to:

• Increased gastrointestinal motility by enhancing peristalsis and gastric emptying

• Reduced nausea and vomiting without significant sedation

• Improved tolerance of oral feeding in children with gastrointestinal disturbances

Its selective peripheral action ensures minimal central nervous system side effects, which is particularly important in the pediatric population.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The drops should be administered using a calibrated dropper for precise dosing. The typical dose is 0.2–0.3 mg/kg body weight per administration, given 3 times daily before meals. Dosage adjustments may be necessary depending on the child’s age, weight, and severity of symptoms. Always follow a physician’s instructions and avoid exceeding the recommended dose.

Benefits of Don-A Pediatric Drop 5 mg/ml

• Safe and effective relief from nausea and vomiting in children

• Enhances gastric motility and improves digestion

• Precise liquid dosing suitable for infants and young children

• Minimizes central nervous system side effects

• Supports better feeding tolerance in children with gastrointestinal disorders

• Convenient dropper administration ensures accuracy and ease

Precautions and Warnings

• Use only under medical supervision

• Not recommended in children under 1 year of age unless prescribed

• Caution in children with heart rhythm disorders or liver disease

• Monitor for rare side effects such as abdominal cramps, diarrhea, or headache

• Avoid use with medications that may prolong the QT interval

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

• Shake well before each use

Pharmaceutical Category

Gastrointestinal Prokinetic / Antiemetic.