Ferimax Injection 100 mg/5 ml is a parenteral iron preparation containing Iron Sucrose, designed to treat iron deficiency and iron deficiency anemia when oral iron therapy is ineffective, poorly tolerated, or contraindicated. It is particularly useful in patients requiring rapid replenishment of iron stores, such as those with chronic kidney disease, significant blood loss, malabsorption syndromes, or anemia associated with pregnancy.

Iron is a crucial component of hemoglobin, myoglobin, and various enzymes involved in oxygen transport and energy metabolism. Iron deficiency can lead to fatigue, pallor, reduced exercise tolerance, and cognitive impairment. Ferimax Injection bypasses the gastrointestinal tract, allowing immediate availability of iron for hemoglobin synthesis and restoration of iron stores, thereby improving patient symptoms and quality of life.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Iron Sucrose

• Strength: 100 mg elemental iron per 5 ml

• Dosage Form: Injection

• Route of Administration: Intravenous

Therapeutic Class

• Hematinics

• Parenteral Iron Preparations

Indications

Ferimax Injection 100 mg/5 ml is indicated for the treatment of iron deficiency and iron deficiency anemia in the following conditions:

• Chronic kidney disease, including patients on hemodialysis

• Patients who cannot tolerate oral iron or in whom oral iron is ineffective

• Rapid correction of iron deficiency anemia

• Pregnancy and postpartum anemia (when oral therapy is unsuitable)

• Anemia due to chronic blood loss or malabsorption

• Iron deficiency in patients preparing for major surgery

Pharmacology

Iron Sucrose is a stable iron–carbohydrate complex that delivers iron in a controlled and safe manner. Following intravenous administration, iron dissociates from the sucrose complex and binds to transferrin in the plasma. Transferrin transports iron to the bone marrow and other tissues where it is incorporated into hemoglobin and stored as ferritin.

Compared to other intravenous iron formulations, Iron Sucrose has a lower risk of serious hypersensitivity reactions and allows multiple doses to be administered safely over a treatment course.

Dosage and Administration

• Administered intravenously by slow injection or infusion under medical supervision.

• Dosage and frequency are determined based on the patient’s iron deficit, body weight, and hemoglobin levels.

• Avoid intramuscular administration due to tissue irritation and poor absorption.

• Monitor hemoglobin, ferritin, and transferrin saturation during therapy to assess response and adjust dosing if needed.

Contraindications

• Hypersensitivity to Iron Sucrose or any component of the formulation

• Iron overload disorders such as hemochromatosis

• Anemia not caused by iron deficiency

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Administer under medical supervision with access to facilities for treating hypersensitivity reactions

• Use caution in patients with liver disease or active infection

• Monitor vital signs during infusion, particularly in patients with cardiovascular disease

• Avoid rapid administration to reduce the risk of hypotension

Side Effects

Ferimax Injection is generally well tolerated. Adverse effects may include:

• Hypotension or transient blood pressure changes

• Nausea, vomiting, or abdominal discomfort

• Headache, dizziness, or fatigue

• Mild local reactions at the injection site

• Rarely, hypersensitivity reactions including rash, pruritus, or anaphylaxis

Use in Pregnancy and Lactation

• Can be administered during pregnancy if clinically indicated

• Considered safe in lactating mothers, as minimal iron is excreted into breast milk

Storage Conditions

• Store below 30°C

• Protect from light

• Do not freeze

• Keep out of reach of children