Dclot Tablet 75 mg contains Clopidogrel Bisulphate, an antiplatelet medication widely used to prevent blood clots in patients at risk of cardiovascular events. It is particularly effective in reducing the risk of heart attack, stroke, and peripheral arterial disease in individuals with a history of atherosclerosis or acute coronary syndrome. Clopidogrel works by inhibiting platelet aggregation, ensuring smoother blood flow and lowering the risk of clot formation in arteries. Dclot Tablet 75 mg is an oral formulation intended for once-daily use, providing consistent antiplatelet protection for long-term cardiovascular health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Clopidogrel Bisulphate 75 mg

• Dosage Form: Oral tablet

• Route of Administration: Oral

Mechanism of Action

Clopidogrel is a platelet aggregation inhibitor that selectively blocks the ADP (adenosine diphosphate) P2Y12 receptor on platelet surfaces:

• Prevents ADP-mediated activation of the glycoprotein IIb/IIIa complex, which is crucial for platelet aggregation

• Reduces platelet clumping, thereby lowering the risk of arterial thrombosis

• Helps maintain smooth blood flow in arteries, preventing blockages that can lead to heart attacks or strokes

Clopidogrel does not dissolve existing clots but prevents the formation of new thrombi, making it a key drug in secondary prevention of cardiovascular events.

Indications

Dclot Tablet 75 mg is indicated for:

• Prevention of myocardial infarction (heart attack) in patients with a history of coronary artery disease

• Reduction of stroke risk in patients with a history of ischemic stroke or transient ischemic attack (TIA)

• Prevention of arterial thrombotic events in patients with peripheral arterial disease

• Use in patients with acute coronary syndrome (unstable angina or non-ST elevation myocardial infarction) in combination with aspirin, where dual antiplatelet therapy is indicated

• Long-term secondary prevention in patients at high cardiovascular risk

Dosage and Administration

• Recommended dose: 75 mg once daily, orally, with or without food

• Swallow the tablet whole with water; do not crush, chew, or split

• Consistency in daily intake is critical for optimal antiplatelet effect

• Duration of therapy is usually long-term or as prescribed by a healthcare professional, especially in patients with prior cardiovascular events

Contraindications

Dclot Tablet 75 mg should not be used in:

• Patients with hypersensitivity to Clopidogrel or any component of the tablet

• Active pathological bleeding (e.g., peptic ulcer, intracranial hemorrhage)

• Severe liver dysfunction with elevated bleeding risk

• Patients undergoing urgent surgery where increased bleeding risk is unacceptable

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Increased risk of bleeding, including gastrointestinal and intracranial hemorrhage

• Inform your doctor before surgery or dental procedures

• Caution in patients with renal or hepatic impairment

• Avoid concomitant use with drugs that significantly increase bleeding risk unless prescribed

• Report signs of unusual bruising, prolonged bleeding, or black stools immediately

Possible Side Effects

Common side effects of Dclot Tablet include:

• Gastrointestinal disturbances: nausea, vomiting, diarrhea, abdominal pain

• Minor bleeding or bruising

• Rare but serious: gastrointestinal bleeding, intracranial hemorrhage, or thrombotic thrombocytopenic purpura (TTP)

Storage

Store in a cool, dry place below 30°C. Protect from moisture and light. Keep out of reach of children.

Conclusion

Dclot Tablet 75 mg is an effective antiplatelet agent for preventing cardiovascular and cerebrovascular events in at-risk patients. By inhibiting platelet aggregation, it reduces the likelihood of heart attacks, strokes, and arterial blockages. With once-daily dosing, Dclot Tablet 75 mg is convenient, safe, and an essential component of long-term cardiovascular risk management under medical supervision.