Progel Vaginal Gel 8% contains Micronized Progesterone, a natural hormone essential for regulating the menstrual cycle and supporting pregnancy. This vaginal gel is specially formulated to deliver progesterone directly to the target site, ensuring optimal absorption and therapeutic efficacy. Progel is widely used in gynecological and reproductive medicine to support luteal phase insufficiency, assisted reproductive technologies, and other conditions where progesterone supplementation is required.

Progesterone plays a key role in preparing the endometrium (uterine lining) for implantation of a fertilized egg and maintaining a healthy pregnancy. Vaginal administration of micronized progesterone allows rapid local absorption, bypassing extensive liver metabolism, which occurs with oral formulations. This results in higher bioavailability, consistent hormone levels, and improved treatment outcomes.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each gram of Progel Vaginal Gel contains:

• Progesterone (Micronized) 80 mg (8%)

Indications

Progel Vaginal Gel 8% is indicated for:

• Luteal phase support in women undergoing in vitro fertilization (IVF) or other assisted reproductive techniques (ART)

• Treatment of luteal phase deficiency in women experiencing infertility

• Support of early pregnancy in cases of recurrent miscarriage due to progesterone deficiency

• Management of menstrual irregularities related to progesterone insufficiency

• Hormonal therapy in certain gynecological conditions as prescribed by a physician

Mechanism of Action

Progesterone, the active hormone in Progel Vaginal Gel, works by:

• Preparing the endometrium for implantation of the fertilized egg

• Maintaining the uterine lining throughout early pregnancy

• Modulating the immune environment in the uterus to support embryo acceptance

• Supporting normal menstrual cycles by regulating the luteal phase

The vaginal route ensures that the hormone reaches the target tissues efficiently, maximizing therapeutic effects while minimizing systemic side effects.

Dosage and Administration

• Use the gel intravaginally using the applicator provided or as directed by your healthcare provider.

• The typical dose is 90–180 mg (1–2 applicators) daily, often divided into one or two applications.

• Apply the gel at the same time each day, preferably in the evening, to maintain consistent hormone levels.

• Continue use for the duration prescribed, typically until the end of the luteal phase or early pregnancy, depending on the indication.

Precautions and Warnings

• For vaginal use only; avoid contact with eyes.

• Not intended as a contraceptive; use other methods if contraception is desired.

• Inform your doctor if you have a history of hormone-sensitive cancers, liver disease, or abnormal uterine bleeding.

• Use with caution in women with a history of thromboembolic disorders.

• Consult your healthcare provider before use during early pregnancy or breastfeeding.

Possible Side Effects

Progel Vaginal Gel is generally well tolerated. Mild side effects may include:

• Vaginal irritation or burning

• Mild discharge

• Headache or breast tenderness

• Temporary bloating or mild abdominal discomfort

Severe allergic reactions are rare but require immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Instructions

• Store below 30°C in a cool, dry place.

• Keep the tube tightly closed and protect from light.

• Keep out of reach of children.

Conclusion

Progel Vaginal Gel 8% (Progesterone Micronized) is an effective and convenient solution for luteal phase support, fertility treatments, and progesterone supplementation. With proper medical supervision and adherence to prescribed dosing, it helps improve reproductive outcomes, maintain early pregnancy, and regulate hormonal balance.