Fixolin Syrup 100 mg/5 ml contains Doxophylline, a bronchodilator belonging to the methylxanthine class, used for the management of respiratory conditions associated with reversible airway obstruction. This syrup formulation is especially suitable for pediatric patients and adults who prefer liquid dosage forms, ensuring ease of administration and accurate dosing.

Doxophylline is known for providing effective bronchodilation with a better safety profile compared to traditional xanthines such as theophylline. It helps relax bronchial smooth muscles, improve airflow, and reduce symptoms such as wheezing, breathlessness, and chest tightness.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fixolin Syrup 100 mg/5 ml is indicated for:

• Bronchial asthma

• Chronic obstructive pulmonary disease

• Chronic bronchitis

• Emphysema

• Other respiratory conditions associated with bronchospasm

Pharmacological Action

Doxophylline acts by inhibiting phosphodiesterase enzymes, leading to an increase in intracellular cyclic AMP levels. This results in relaxation of bronchial smooth muscles and sustained bronchodilation. It also improves diaphragmatic contractility and exhibits mild anti-inflammatory effects. Unlike theophylline, Doxophylline has minimal action on adenosine receptors, reducing the likelihood of cardiac and central nervous system adverse effects.

Dosage and Administration

• Dosage is determined by the patient’s age, body weight, and clinical condition.

• Fixolin Syrup is administered orally and may be taken with or without food.

• Patients should follow the prescribed dosing schedule carefully.

• Prolonged use should be monitored by a healthcare professional.

Benefits

• Effective relief from bronchospasm

• Suitable for children and patients who have difficulty swallowing tablets

• Improved safety and tolerability profile

• Supports long-term management of asthma and COPD

• Convenient and palatable liquid formulation

Side Effects

Common side effects may include:

• Nausea

• Vomiting

• Headache

• Gastric irritation

• Mild dizziness

These effects are generally mild and temporary when taken at recommended doses.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with heart disease, liver impairment, or peptic ulcer

• Not recommended during pregnancy and breastfeeding unless clearly necessary

• Avoid excessive consumption of caffeine-containing products

• Regular follow-up is advised during long-term therapy

Drug Interactions

Doxophylline may interact with certain antibiotics, anticonvulsants, and other bronchodilators. Patients should inform their healthcare provider about all medications they are using.

Storage

Store below 30°C in a dry place. Protect from light. Keep out of reach of children.

Fixolin Syrup 100 mg/5 ml offers reliable bronchodilator therapy with enhanced tolerability, making it an effective option for managing chronic respiratory conditions in both pediatric and adult patients.